[HTML][HTML] The dynamics of nerve degeneration and regeneration in a healthy milieu and in diabetes
LB Dahlin - International Journal of Molecular Sciences, 2023 - mdpi.com
Appropriate animal models, mimicking conditions of both health and disease, are needed to
understand not only the biology and the physiology of neurons and other cells under normal …
understand not only the biology and the physiology of neurons and other cells under normal …
Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration
Following acute injury, the capillary vascular bed in the lung must be repaired to reestablish
gas exchange with the external environment. Little is known about the transcriptional and …
gas exchange with the external environment. Little is known about the transcriptional and …
Intrinsic heterogeneity in axon regeneration
XQ Fu, WR Zhan, WY Tian, DD Cao… - Biochemical Society …, 2022 - portlandpress.com
The nervous system is composed of a variety of neurons and glial cells with different
morphology and functions. In the mammalian peripheral nervous system (PNS) or the lower …
morphology and functions. In the mammalian peripheral nervous system (PNS) or the lower …
[HTML][HTML] Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans
Spinal motor neurons have been implicated in the loss of motor function that occurs with
advancing age. However, the cellular and molecular mechanisms that impair the function of …
advancing age. However, the cellular and molecular mechanisms that impair the function of …
[HTML][HTML] The transcription factor Ets1 influences axonal growth via regulation of Lcn2
M Gu, X Li, R Wu, X Cheng, S Zhou, X Gu - Molecular Neurobiology, 2024 - Springer
Transcription factors are essential for the development and regeneration of the nervous
system. The current study investigated key regulatory transcription factors in rat spinal cord …
system. The current study investigated key regulatory transcription factors in rat spinal cord …
Transcriptional regulation and signaling of type IV IFN with identification of the ISG repertoire in an amphibian model, Xenopus laevis
SN Chen, B Li, Z Gan, KL Wang, L Li… - The Journal of …, 2023 - journals.aai.org
Abstract The type IV IFN (IFN-υ) is reported in vertebrates from fish to primary mammals with
IFN-υR1 and IL-10R2 as receptor subunits. In this study, the proximal promoter of IFN-υ was …
IFN-υR1 and IL-10R2 as receptor subunits. In this study, the proximal promoter of IFN-υ was …
[HTML][HTML] Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape
Q Li, J Chen, P Faux, ME Delgado, B Bonfante… - Communications …, 2023 - nature.com
We report a genome-wide association study of facial features in> 6000 Latin Americans
based on automatic landmarking of 2D portraits and testing for association with inter …
based on automatic landmarking of 2D portraits and testing for association with inter …
[HTML][HTML] MSC-derived mitochondria promote axonal regeneration via Atf3 gene up-regulation by ROS induced DNA double strand breaks at transcription initiation …
Y Zhang, T Xu, J Xie, H Wu, W Hu, X Yuan - Cell Communication and …, 2024 - Springer
Background The repair of peripheral nerve injury poses a clinical challenge, necessitating
further investigation into novel therapeutic approaches. In recent years, bone marrow …
further investigation into novel therapeutic approaches. In recent years, bone marrow …
[HTML][HTML] Lampreys and spinal cord regeneration:“a very special claim on the interest of zoologists,” 1830s-present
K Maxson Jones, JR Morgan - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Employing history of science methods, including analyses of the scientific literature, archival
documents, and interviews with scientists, this paper presents a history of lampreys in …
documents, and interviews with scientists, this paper presents a history of lampreys in …
Activating transcription factor 3 stimulates follicle-stimulating hormone-β expression in vitro but is dispensable for follicle-stimulating hormone production in murine …
CAI Alonso, CD David, C Toufaily, Y Wang… - …, 2023 - academic.oup.com
Abstract Follicle-stimulating hormone (FSH), a dimeric glycoprotein produced by pituitary
gonadotrope cells, regulates spermatogenesis in males and ovarian follicle growth in …
gonadotrope cells, regulates spermatogenesis in males and ovarian follicle growth in …