Calcium dysregulation in heart diseases: Targeting calcium channels to achieve a correct calcium homeostasis

G Morciano, A Rimessi, S Patergnani, VAM Vitto… - Pharmacological …, 2022 - Elsevier
Intracellular calcium signaling is a universal language source shared by the most part of
biological entities inside cells that, all together, give rise to physiological and functional …

Chronic ethanol exposure induces deleterious changes in cardiomyocytes derived from human induced pluripotent stem cells

R Liu, F Sun, LC Armand, R Wu, C Xu - Stem cell reviews and reports, 2021 - Springer
Chronic alcohol consumption in adults can induce cardiomyopathy, arrhythmias, and heart
failure. In newborns, prenatal alcohol exposure can increase the risk of congenital heart …

Multi-omics approach reveals dysregulation of protein phosphorylation correlated with lipid metabolism in mouse non-alcoholic fatty liver

SQ Kim, R Mohallem, J Franco, KK Buhman, KH Kim… - Cells, 2022 - mdpi.com
Obesity caused by overnutrition is a major risk factor for non-alcoholic fatty liver disease
(NAFLD). Several lipid intermediates such as fatty acids, glycerophospholipids and …

Carfilzomib treatment causes molecular and functional alterations of human induced pluripotent stem cell–derived cardiomyocytes

P Forghani, A Rashid, F Sun, R Liu, D Li… - Journal of the …, 2021 - Am Heart Assoc
Background Anticancer therapies have significantly improved patient outcomes; however,
cardiac side effects from cancer therapies remain a significant challenge. Cardiotoxicity …

[HTML][HTML] CPNE1 silencing inhibits cell proliferation and accelerates apoptosis in human gastric cancer

Y Li, L Li, H Liu, T Zhou - European Journal of Pharmaceutical Sciences, 2022 - Elsevier
Gastric cancer is a heterogeneous disease accompanied by the alteration of various
causative genes. The discovery of molecular targets and potential mechanisms of gastric …

Chronic ethanol exposure induces mitochondrial dysfunction and alters gene expression and metabolism in human cardiac spheroids

H Hwang, R Liu, R Eldridge, X Hu… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Chronic alcohol consumption in adults can induce various cardiac toxicities
such as arrhythmias, cardiomyopathy, and heart failure. Prenatal alcohol exposure can …

Synergistic Effects of Ethanol and G-Coupled Inwardly Rectifying Potassium Channel Subunit 2 on Neuronal Excitability and Mitochondria

IA Prytkova - 2023 - search.proquest.com
Genome-wide association analysis of electroencephalographic endophenotypes for alcohol
use disorder has identified non-coding polymorphisms within the KCNJ6 gene. KCNJ6 …