The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine
production, viral RNA and a sustained interferon (IFN) response, all of which are …

The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Background Prominent clinical symptoms of COVID-19 include CNS manifestations.
However, it is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Chest CT has a potential role in the diagnosis, detection of complications, and
prognostication of coronavirus disease 2019 (COVID-19). Implementation of appropriate …

SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets
multiple organs and causes severe coagulopathy. Histopathological organ changes might …

Abstract SARS-CoV-2, the etiologic agent of COVID-19, is a global pandemic with
substantial mortality dominated by acute respiratory distress syndrome. We systematically …

A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with
the pathogenesis of other viral infections. Biological sex differences may manifest …