Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients
L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …
Viral infections in HSCT: detection, monitoring, clinical management, and immunologic implications
C Annaloro, F Serpenti, G Saporiti, G Galassi… - Frontiers in …, 2021 - frontiersin.org
In spite of an increasing array of investigations, the relationships between viral infections
and allogeneic hematopoietic stem cell transplantation (HSCT) are still controversial, and …
and allogeneic hematopoietic stem cell transplantation (HSCT) are still controversial, and …
Cytomegalovirus-specific T-cell reconstitution following letermovir prophylaxis after hematopoietic cell transplantation
D Zamora, ER Duke, H Xie, BC Edmison… - Blood, The Journal …, 2021 - ashpublications.org
Decreased cytomegalovirus (CMV)-specific immunity after hematopoietic cell transplantation
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …
Effect of preemptive therapy vs antiviral prophylaxis on cytomegalovirus disease in seronegative liver transplant recipients with seropositive donors: a randomized …
N Singh, DJ Winston, RR Razonable, GM Lyon… - Jama, 2020 - jamanetwork.com
Importance Despite the use of a cytomegalovirus (CMV) prevention strategy of antiviral
prophylaxis for high-risk CMV-seronegative liver transplant recipients with seropositive …
prophylaxis for high-risk CMV-seronegative liver transplant recipients with seropositive …
Poxvirus vectored cytomegalovirus vaccine to prevent cytomegalovirus viremia in transplant recipients: a phase 2, randomized clinical trial
I Aldoss, C La Rosa, LR Baden, J Longmate… - Annals of internal …, 2020 - acpjournals.org
Background: Triplex vaccine was developed to enhance cytomegalovirus (CMV)–specific T
cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT) …
cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT) …
Clinical “real‐world” experience with letermovir for prevention of cytomegalovirus infection in allogeneic hematopoietic cell transplant recipients
Background Letermovir was approved in 2017 for prevention of cytomegalovirus (CMV)
infection in seropositive (R+) allogeneic hematopoietic cell transplantation (HCT) patients …
infection in seropositive (R+) allogeneic hematopoietic cell transplantation (HCT) patients …
Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation
L Stern, HM McGuire, S Avdic… - Nature …, 2022 - nature.com
Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic
haematopoietic stem cell transplantation and has a complex relationship with post …
haematopoietic stem cell transplantation and has a complex relationship with post …
Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine …
R Rogers, K Saharia, A Chandorkar, ZF Weiss… - BMC infectious …, 2020 - Springer
Background Cytomegalovirus (CMV) infection is one of the most common opportunistic
infections following organ transplantation, despite administration of CMV prophylaxis. CMV …
infections following organ transplantation, despite administration of CMV prophylaxis. CMV …
Robust CD4+ T-cell recovery in adults transplanted with cord blood and no antithymocyte globulin
Quality of immune reconstitution after cord blood transplantation (CBT) without
antithymocyte globulin (ATG) in adults is not established. We analyzed immune recovery in …
antithymocyte globulin (ATG) in adults is not established. We analyzed immune recovery in …
Immune control of cytomegalovirus reactivation in stem cell transplantation
MA Degli-Esposti, GR Hill - Blood, The Journal of the American …, 2022 - ashpublications.org
The reactivation of viruses from latency after allogeneic stem cell transplantation (SCT)
continues to represent a major clinical challenge requiring sophisticated monitoring …
continues to represent a major clinical challenge requiring sophisticated monitoring …