Elevated systolic blood pressure and risk of cardiovascular and renal disease: overview of evidence from observational epidemiologic studies and randomized …

J He, PK Whelton - American heart journal, 1999 - Elsevier
The effect of elevated blood pressure on risk of cardiovascular and renal disease has been
documented in both observational epidemiologic studies and clinical trials. However, these …

Risk factors and cardiovascular disease in Turkey

A Onat - Atherosclerosis, 2001 - Elsevier
Cardiovascular risk factors as well as morbidity and mortality from coronary heart disease
among Turkish adults are herein reviewed. Lipids and lipoproteins are in focus, but other …

Complement C3 and cleavage products in cardiometabolic risk

A Onat, G Can, R Rezvani, K Cianflone - Clinica chimica acta, 2011 - Elsevier
This review summarizes available evidence on the role of serum complement component 3
(C3), produced by liver, adipocytes and activated macrophages at inflammation sites, and …

Evaluation of coronary artery disease by computed tomography angiography in patients treated for childhood Hodgkin's lymphoma

S Küpeli, T Hazırolan, A Varan, D Akata… - Journal of clinical …, 2010 - ascopubs.org
Purpose To detect pathologies in coronary arteries by computed tomography angiography
(CTA) in survivors of childhood Hodgkin's lymphoma who have been treated with …

Methylene tetrahydrofolate reductase genotype and the risk and extent of coronary artery disease in a population with low plasma folate

SL Tokgözoğlu, M Alikaşifoğlu, E Atalar, K Aytemir… - Heart, 1999 - heart.bmj.com
OBJECTIVE To determine the effects of the thermolabile methylene tetrahydrofolate
reductase (MTHFR) mutation on the presence and extent of coronary atherosclerosis in a …

Low-grade inflammation, and dysfunction of high-density lipoprotein and its apolipoproteins as a major driver of cardiometabolic risk

A Onat, G Hergenç - Metabolism, 2011 - Elsevier
Dysfunction of high-density lipoprotein (HDL) particles that even become proinflammatory or
lose atheroprotective properties is known through analyses of HDL isolated from diabetic …

Waist circumference and waist-to-hip ratio in Turkish adults: interrelation with other risk factors and association with cardiovascular disease

A Onat, V Sansoy, Ö Uysal - International journal of cardiology, 1999 - Elsevier
Objective: To investigate the distribution of waist circumference (WC) and waist-to-hip ratio
(WHR), their relationships with a number of established risk factors and their relevance to …

The paradox of high apolipoprotein AI levels independently predicting incident type-2 diabetes among Turks

A Onat, G Hergenç, S Bulur, M Uğur… - International journal of …, 2010 - Elsevier
BACKGROUND: Predictive value of apolipoprotein (apo) AI for incident hypertension,
metabolic syndrome (MetS), type 2 diabetes (DM) and coronary heart disease (CHD) needs …

Risk determination of dyslipidemia in populations characterized by low levels of high-density lipoprotein cholesterol

TP Bersot, GM Pépin, RW Mahley - American Heart Journal, 2003 - Elsevier
BACKGROUND: Current guidelines for managing dyslipidemia qualify patients for treatment
based on low-density lipoprotein cholesterol (LDL-C) levels and other risk factors for …

Atherosclerotic vascular disease and risk factors in Turkey: from past to present

L Tokgözoǧlu, EB Kaya - Journal of atherosclerosis and thrombosis, 2008 - jstage.jst.go.jp
The prevalance of atherosclerotic vascular disease is unexpectedly high in Turkey despite
its young population, with a median age of 29. The mean total cholesterol is lower than in …