The term B-factor, sometimes called the Debye–Waller factor, temperature factor, or atomic
displacement parameter, is used in protein crystallography to describe the attenuation of X …

The consensus sequence approach to predicting stabilizing substitutions in proteins rests on
the notion that conserved amino acids are more likely to contribute to the stability of a protein …

Polyethylene terephthalate (PET) is a mass‐produced petroleum‐based synthetic polymer.
Enzymatic PET degradation using, for example, Ideonella sakaiensis PETase (IsPETase) …

Chitinase is a promising biocatalyst for chitin biotransformation in the field of recalcitrant
biomass degradation. Excellent catalytic performance is conducive to its commercial …

Recently, a bacterium strain of Ideonella sakaiensis was identified with the uncommon
ability to degrade the poly (ethylene terephthalate)(PET). The PETase from I. sakaiensis …

Dynamic motions of enzymes occurring on a broad range of timescales play a pivotal role in
all steps of the reaction pathway, including substrate binding, catalysis, and product release …

The combinatorial space of an enzyme sequence has astronomical possibilities and
exploring it with contemporary experimental techniques is arduous and often ineffective …

Transaminases that promote the amination of ketones into amines are an emerging class of
biocatalysts for preparing a series of drugs and their intermediates. One of the main …

The rapid growth of sequence databases over the past two decades means that protein
engineers faced with optimizing a protein for any given task will often have immediate …

Accounting for nearly two-thirds of known druggable targets, membrane proteins are highly
relevant for cell physiology and pharmacology. In this regard, the structural determination of …