Hypoxic pulmonary vasoconstriction
JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport
J Lytton - Biochemical Journal, 2007 - portlandpress.com
Mammalian Na+/Ca2+ exchangers are members of three branches of a much larger family
of transport proteins [the CaCA (Ca2+/cation antiporter) superfamily] whose main role is to …
of transport proteins [the CaCA (Ca2+/cation antiporter) superfamily] whose main role is to …
The vascular Na, K-ATPase: clinical implications in stroke, migraine, and hypertension
In the vascular wall, the Na, K-ATPase plays an important role in the control of arterial tone.
Through cSrc signaling, it contributes to the modulation of Ca2+ sensitivity in vascular …
Through cSrc signaling, it contributes to the modulation of Ca2+ sensitivity in vascular …
Ca2+ homeostasis and structural and functional remodelling of airway smooth muscle in asthma
K Mahn, OO Ojo, G Chadwick, PI Aaronson, JPT Ward… - Thorax, 2010 - thorax.bmj.com
Asthma is characterised by airway hyper-responsiveness and remodelling, and there is
mounting evidence that alterations in the phenotype of airway smooth muscle (ASM) play a …
mounting evidence that alterations in the phenotype of airway smooth muscle (ASM) play a …
[HTML][HTML] Regulation of plasma membrane calcium fluxes by mitochondria
N Demaurex, D Poburko, M Frieden - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
The role of mitochondria in cell signaling is becoming increasingly apparent, to an extent
that the signaling role of mitochondria appears to have stolen the spotlight from their primary …
that the signaling role of mitochondria appears to have stolen the spotlight from their primary …
[HTML][HTML] Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated …
V Tedeschi, MJ Sisalli, A Pannaccione, I Piccialli… - Cell Calcium, 2022 - Elsevier
Abstract Excessive calcium (Ca 2+) release from the endoplasmic reticulum (ER) represents
an important hallmark of several neurodegenerative diseases. ER is recharged from Ca 2+ …
an important hallmark of several neurodegenerative diseases. ER is recharged from Ca 2+ …
Coupling of mitochondria to store-operated Ca2+-signaling sustains constitutive activation of protein kinase B/Akt and augments survival of malignant melanoma cells
B Feldman, S Fedida-Metula, J Nita, I Sekler… - Cell calcium, 2010 - Elsevier
Mitochondria are emerging as a major hub for cellular Ca2+-signaling, though their
contribution to Ca2+-driven growth-and survival-promoting events in cancer is poorly …
contribution to Ca2+-driven growth-and survival-promoting events in cancer is poorly …
Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na+/Ca2+ exchanger on cell proliferation in human cardiac fibroblasts: Effects of …
K Ikeda, T Nakajima, Y Yamamoto, N Takano… - Cell Calcium, 2013 - Elsevier
Expression of transient receptor potential canonical channels (TRPC) and the effects of
transforming growth factor-β1 (TGF-β1) on Ca 2+ signals and fibroblast proliferation were …
transforming growth factor-β1 (TGF-β1) on Ca 2+ signals and fibroblast proliferation were …