Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma
Abstract Background Glioblastomas (GBMs) are central nervous system tumors that resist
standard-of-care interventions and even immune checkpoint blockade. Myeloid cells in the …
standard-of-care interventions and even immune checkpoint blockade. Myeloid cells in the …
[HTML][HTML] A novel inflammation-related signature for predicting prognosis and characterizing the tumor microenvironment in colorectal cancer
J Li, J Yang, R Xing, Y Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Inflammation is a critical component of tumor progression, and it modifies the tumor
microenvironment by various mechanisms. Here, we explore the effect of the inflammatory …
microenvironment by various mechanisms. Here, we explore the effect of the inflammatory …
CD13 expression affects glioma patient survival and influences key functions of human glioblastoma cell lines in vitro
W Zhang, A Blank, I Kremenetskaia, A Nitzsche… - BMC cancer, 2024 - Springer
CD13 (APN) is an Alanyl-Aminopeptidase with diverse functions. The role of CD13 for
gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA …
gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA …
Interactions between microglia and glioma in tumor microenvironment
JC Tao, D Yu, W Shao, DR Zhou, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Gliomas, the most prevalent primary tumors in the central nervous system, are marked by
their immunosuppressive properties and consequent poor patient prognosis. Current …
their immunosuppressive properties and consequent poor patient prognosis. Current …
Characterization and optimization of the tumor microenvironment in patient-derived organotypic slices and organoid models of glioblastoma
V Nickl, J Eck, N Goedert, J Hübner, T Nerreter… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is the most common malignant brain tumor in adults,
entailing a very short survival. New therapeutic strategies are desperately needed …
entailing a very short survival. New therapeutic strategies are desperately needed …
[引用][C] Characterization and Optimization of the Tumor Microenvironment in Patient-Derived Organotypic Slices and Organoid Models of Glioblastoma. Cancers 2023 …
V Nickl, J Eck, N Goedert, J Hübner, T Nerreter… - 2023