Epigenetic developmental mechanisms underlying sex differences in cancer

JB Rubin, T Abou-Antoun, JE Ippolito, L Llaci… - The Journal of Clinical …, 2024 - jci.org
Cancer risk is modulated by hereditary and somatic mutations, exposures, age, sex, and
gender. The mechanisms by which sex and gender work alone and in combination with …

Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma

SC Massey, P Whitmire, TE Doyle, JE Ippolito… - Cancer letters, 2021 - Elsevier
The influence of biological sex differences on human health and disease, while being
increasingly recognized, has long been underappreciated and underexplored. While …

Why is oocyte aneuploidy increased with maternal aging?

JY Ma, S Li, LN Chen, H Schatten, XH Ou… - Journal of genetics and …, 2020 - Elsevier
One of the main causes of pregnancy failure and fetus abortion is oocyte aneuploidy, which
is increased with maternal aging. Numerous possible causes of oocyte aneuploidy in aged …

Sex as a biological variable in tissue engineering and regenerative medicine

JB Allen, C Ludtka, BD James - Annual review of biomedical …, 2023 - annualreviews.org
Although sex differences have been noted in cellular function and behavior, therapy efficacy,
and disease incidence and outcomes, the adoption of sex as a biological variable in tissue …

Update on the clinical perspectives and care of the child with 47, XXY (Klinefelter Syndrome)

CA Samango-Sprouse, DR Counts… - The application of …, 2019 - Taylor & Francis
Abstract 47, XXY (Klinefelter syndrome [KS]) is the most common sex chromosomal
aneuploidy (1: 660), yet, despite this, only 25% of the males are ever diagnosed. Males with …

The benefits and limitations of cell‐free DNA screening for 47, XXY (Klinefelter syndrome)

C Samango‐Sprouse, C Keen, T Sadeghin… - Prenatal …, 2017 - Wiley Online Library
Objective The purpose of this paper is to provide an overview of the 47, XXY syndrome,
which is the most commonly occurring X and Y chromosomal variation. This paper seeks to …

Impact of early diagnosis and noninvasive prenatal testing (NIPT): knowledge, attitudes, and experiences of parents of children with sex chromosome aneuploidies …

CA Samango‐Sprouse, GF Porter… - Prenatal …, 2020 - Wiley Online Library
Objective To investigate the attitudes of parents of children with a sex chromosome
aneuploidy (SCA) regarding the impact of an early diagnosis and noninvasive prenatal …

Women are not adult human females

R Mason - Australasian Journal of Philosophy, 2024 - Taylor & Francis
Full article: Women Are Not Adult Human Females Skip to Main Content Taylor and Francis
Online homepage Taylor and Francis Online homepage Log in | Register Cart 1.Home 2.All …

Diagnostic cytogenetic testing following positive noninvasive prenatal screening results of sex chromosome abnormalities: report of five cases and systematic review …

X Xie, W Tan, F Li, E Carrano, P Ramirez… - … Genetics & Genomic …, 2020 - Wiley Online Library
Background Follow‐up cytogenetic analysis has been recommended for cases with positive
noninvasive prenatal screening (NIPS) results. This study of five cases with numerical and …

Multicenter clinical experience with non‐invasive cell‐free DNA screening for monosomy X and related X‐chromosome variants

I Bedei, T Gehrke, KP Gloning… - Prenatal …, 2023 - Wiley Online Library
Objective We aimed to investigate how the presence of fetal anomalies and different X
chromosome variants influences Cell‐free DNA (cfDNA) screening results for monosomy X …