Dipolar aprotic and ethereal solvents comprise just over 40% of all organic solvents utilized
in synthetic organic, medicinal, and process chemistry. Unfortunately, many of the common …

Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and
Medicinal Chemistry | Chemical Reviews ACS ACS Publications C&EN CAS Find my …

Green chemistry has become a hot topic and the focus of not only many companies but also
researchers. Green chemistry strives to identify alternative and environmentally friendly …

Dihydrolevoclucosenone (Cyrene is its market name) is a biomass-derived solvent that can
be produced in only two steps from biomass, while being biodegradable, non-mutagenic …

The development of green solvents is one of the key tenets of Green Chemistry as solvents
account for the majority of waste stemming from the production of the chemicals on which we …

Construction of the amide/peptide bond is one of the most encountered transformations in
the pharmaceutical and chemical industries. Traditional protocols rely on the use of …

Cyrene™ as a bio-alternative dipolar aprotic solvent: a waste minimizing and molar efficient
protocol for the synthesis of amides from acid chlorides and primary amines in the bio …

Cyrene (dihydrolevoglucosenone) is a green dipolar aprotic solvent prepared by pyrolysis of
cellulose-containing biomass. Cyrene possesses a beneficial occupational health and …

To replace dimethylformamide (DMF) in fluorenylmethoxycarbonyl (Fmoc) solid-phase
peptide synthesis, we explored the application of mixtures of green solvents (green solvents …

The formation of the amide bond is among the most commonly performed transformations in
the pharmaceutical industry and the wider chemical industry. The current methods for its …