Targeting TNF: a therapeutic strategy for Alzheimer's disease

X Cheng, Y Shen, R Li - Drug discovery today, 2014 - Elsevier
Highlights•TNFα biosynthesis, TNF receptors, and signaling.•Neurotoxicity of TNFα in the
brain.•TNFα receptor signaling-related neuron death and neuroprotection.•TNF receptors …

Fibrinogen interaction with the red blood cell membrane

C Saldanha - Clinical Hemorheology and Microcirculation, 2013 - content.iospress.com
A brief review of the fibrinogen molecule composition and structure is presented like as an
introduction to the effects of this plasma protein on the red blood cell hemorheoplogical …

Development of experimental microfluidic device and methodology for assessing microrheological properties of blood

N Antonova, K Khristov, A Alexandrova… - Clinical …, 2023 - content.iospress.com
METHODS: A new microfluidic device was elaborated, connected to a system, including a
microscope with a digital camera, a pump with a manometer and a computer with specially …

Vinpocetine and pyritinol: a new model for blood rheological modulation in cerebrovascular disorders—a randomized controlled clinical study

HM Alkuraishy, AI Al-Gareeb… - BioMed research …, 2014 - Wiley Online Library
Blood and plasma viscosity are the major factors affecting blood flow and normal circulation.
Whole blood viscosity is mainly affected by plasma viscosity, red blood cell deformability …

Effects of pentoxifylline on hemodynamic, hemorheological, and microcirculatory parameters in young SHRs during arterial hypertension development

MB Plotnikov, OI Aliev, AY Shamanaev… - Clinical and …, 2017 - Taylor & Francis
The most common form of hypertension in young adults is isolated diastolic hypertension.
Diastolic arterial pressure is determined by the total peripheral resistance and depends on …

Association between serum hepcidin‐25 and primary resistance to erythropoiesis‐stimulating agents in chronic kidney disease: a secondary analysis of the HERO …

J Gummer, R Trengove, EM Pascoe, SV Badve… - …, 2017 - Wiley Online Library
Background Pentoxifylline has been shown to increase haemoglobin levels in patients with
chronic kidney disease (CKD) and erythropoietin‐stimulating agent (ESA)‐hyporesponsive …

Relationship between arterial blood pressure and blood viscosity in spontaneously hypertensive rats treated with pentoxifylline

MB Plotnikov, OI Aliev, AV Nosarev… - …, 2016 - content.iospress.com
Background: Systemic arterial pressure (AP) depends on two physiological variables:
cardiac output (CO) and total peripheral resistance (TPR). The latter depends on vascular …

Effects of sarpogrelate on blood viscosity

KS Yum, SG Kang, JW Lee, YI Cho - Microvascular Research, 2023 - Elsevier
The objective of the present study was to evaluate the effects and safety of sarpogrelate
hydrochloride (sarpogrelate) in patients with elevated blood viscosity (BV), after 12 and 24 …

Alterations of haemorheological parameters in patients with peripheral arterial disease

I Ricci, F Sofi, AA Liotta, S Fedi… - Clinical …, 2013 - content.iospress.com
Peripheral arterial disease (PAD), is a common manifestation of systemic atherosclerosis.
Advances on the development of such vascular disease have described with a number of …

[PDF][PDF] 甲襞微循环与颈动脉病变程度相关性研究

张鑫月, 贾振华, 常丽萍 - 中国医科大学学报, 2015 - mzy.ylyy.org
摘要目的研究甲襞微循环与颈动脉粥样硬化病变程度的相关性. 方法将120
例观察对象根据颈动脉彩超检测结果分为: 颈动脉内-中膜(IMT) 正常组(40 例), IMT 增厚组(40 …