Ubiquitination is a highly conserved and fundamental posttranslational modification (PTM) in
all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) …

Contents Summary 901 I. Introduction 901 II. Biochemistry and structure of plant SBTs 902
III. Phylogeny of plant SBTs and family organization 903 IV. Physiological roles of plant SBTs …

Lysosomes clear macromolecules, maintain nutrient and cholesterol homeostasis,
participate in tissue repair, and in many other cellular functions. To assume these tasks …

The molecular mechanisms underlying plastic changes in the strength and connectivity of
excitatory synapses have been studied extensively for the past few decades and remain the …

Background Multiple loci have been identified for coronary artery disease (CAD) by genome-
wide association studies (GWAS), but no such studies on CAD incidence has been reported …

Cellular trafficking between organelles is typically assured by short motifs that contact carrier
proteins to transport them to their destination. The ubiquitin E3 ligase RING finger protein 13 …

Protein quality control is a process in which a protein's folding status is constantly monitored.
Mislocalized proteins (MLP), are processed by the various quality control pathways, as they …

The interactions of extracellular ligands with single membrane spanning receptors, such as
kinases, typically serve to agonise or antagonise the intracellular activation of signalling …

This study investigated modifications to the ubiquitin proteasome system (UPS) in a mouse
model of type 2 diabetes mellitus (T2DM) and their relationship to heart complications. db/db …

The protease‐associated (PA) domain‐containing E3 ubiquitin ligases are transmembrane
proteins located in intracellular organelles such as the endoplasmic reticulum, endosomes …