Asthma remains a major health problem with significant morbidity, mortality and economic
costs. In asthma, airway remodelling, which refers to all the microscopic structural changes …

Asthma is a chronic respiratory condition characterised by episodes of shortness of breath
due to reduced airway flow. The disease is triggered by a hyperreactive immune response to …

The aims of this study were to investigate the effects of Lactobacillus plantarum DR7 isolated
from bovine milk against upper respiratory tract infections (URTI) and elucidate the possible …

Background Clinical trials applying iota-carrageenan nasal spray have previously shown to
reduce duration of virus-confirmed common cold. The present study pooled data of two …

Aim Infant colic is a frequent problem affecting up to 10–30% of infants in first 3 months of
life. Results from previous trials have shown that manipulation of gut microbiota can lead to …

Background Airway epithelial cells (AEC) from patients with asthma, appear to have an
impaired interferon (IFN)-β and-λ response to infection with rhinovirus. Objectives To …

Abstract This 12-months randomized, double-blind and placebo-controlled study aimed at
investigating the effects of Lactobacillus casei Zhang (LCZ; 9 log CFU daily) against upper …

The inflammasome–IL-1 axis and type I interferons (IFNs) have been shown to exert
protective effects upon respiratory tract infections. Conversely, IL-1 has also been implicated …

OBJECTIVE: To review the available literature on the association between acute viral
respiratory tract infection and the onset of asthma exacerbations, identifying the most …

Our understanding on the immunological roles of pathogen recognition in innate immunity
has vastly increased over the past 20 years. Nucleotide-binding oligomerization domain …