Recent advances in lung-on-a-chip models
Highlights•Transition from conventional 2D models to 3D and advanced lung-on-a-chip
models.•Recent advances in lung-on-a-chip platforms and their implementation.•Numerous …
models.•Recent advances in lung-on-a-chip platforms and their implementation.•Numerous …
Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
Targeting the mitochondria in chronic respiratory diseases
DK Chellappan, KR Paudel, NW Tan, KS Cheong… - Mitochondrion, 2022 - Elsevier
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …
the source of respiratory ATP. Recently published studies have demonstrated that …
Evaluation of the Cytotoxic Activity and Anti-Migratory Effect of Berberine–Phytantriol Liquid Crystalline Nanoparticle Formulation on Non-Small-Cell Lung Cancer In …
Non-small-cell lung cancer (NSCLC) is the most common form of lung cancer, which is a
leading cause of cancer-related deaths worldwide. Berberine is an isoquinoline alkaloid that …
leading cause of cancer-related deaths worldwide. Berberine is an isoquinoline alkaloid that …
Dissecting the in vitro fate of plant-derived bioactive encapsulated nanoparticles in lung diseases
Lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung
cancer are prevalent worldwide, with high mortality rates. There are many pathways …
cancer are prevalent worldwide, with high mortality rates. There are many pathways …
Nutraceuticals and mitochondrial oxidative stress: bridging the gap in the management of bronchial asthma
Asthma is a chronic inflammatory disease primarily characterized by inflammation and
reversible bronchoconstriction. It is currently one of the leading causes of morbidity and …
reversible bronchoconstriction. It is currently one of the leading causes of morbidity and …
Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells
Airway remodelling occurs in chronic respiratory diseases (CRDs) such as asthma and
chronic obstructive pulmonary disease (COPD). It is characterized by aberrant activation of …
chronic obstructive pulmonary disease (COPD). It is characterized by aberrant activation of …
Advancements in chitosan-based nanoparticles for pulmonary drug delivery
TM Zacaron, MLS Silva, MP Costa, DM Silva, AC Silva… - Polymers, 2023 - mdpi.com
The evolution of respiratory diseases represents a considerable public health challenge, as
they are among the leading causes of death worldwide. In this sense, in addition to the high …
they are among the leading causes of death worldwide. In this sense, in addition to the high …
Greenness and chronic respiratory health issues: a systematic review and meta-analysis
M Tang, W Liu, H Li, F Li - Frontiers in Public Health, 2023 - frontiersin.org
Introduction The number of chronic respiratory disease (CRD) individuals worldwide has
been continuously increasing. Numerous studies have shown that greenness can improve …
been continuously increasing. Numerous studies have shown that greenness can improve …
Advances in preclinical in vitro models for the translation of precision medicine for cystic fibrosis
The development of preclinical in vitro models has provided significant progress to the
studies of cystic fibrosis (CF), a frequently fatal monogenic disease caused by mutations in …
studies of cystic fibrosis (CF), a frequently fatal monogenic disease caused by mutations in …