[HTML][HTML] Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications

Q Kang, C Yang - Redox biology, 2020 - Elsevier
Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2

M Gheblawi, K Wang, A Viveiros, Q Nguyen… - Circulation …, 2020 - Am Heart Assoc
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …

Gut microbiota and complications of type-2 diabetes

CO Iatcu, A Steen, M Covasa - Nutrients, 2021 - mdpi.com
The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …

The gut microbiome and metabolic syndrome

K Dabke, G Hendrick, S Devkota - The Journal of clinical …, 2019 - Am Soc Clin Investig
The metabolic syndrome (MetS) is a constellation of risk factors that, if left untreated, will
often progress to greater metabolic defects such as type 2 diabetes and nonalcoholic fatty …

The role of inflammation in diabetic retinopathy

JV Forrester, L Kuffova, M Delibegovic - Frontiers in immunology, 2020 - frontiersin.org
Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

[HTML][HTML] Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment

Z Liu, X Dai, H Zhang, R Shi, Y Hui, X Jin… - Nature …, 2020 - nature.com
Cognitive decline is one of the complications of type 2 diabetes (T2D). Intermittent fasting
(IF) is a promising dietary intervention for alleviating T2D symptoms, but its protective effect …

Inflammation: the link between comorbidities, genetics, and Alzheimer's disease

EA Newcombe, J Camats-Perna, ML Silva… - Journal of …, 2018 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

[HTML][HTML] Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

C Gubert, G Kong, T Renoir, AJ Hannan - Neurobiology of disease, 2020 - Elsevier
The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …

[HTML][HTML] The effects of intermittent fasting on brain and cognitive function

J Gudden, A Arias Vasquez, M Bloemendaal - Nutrients, 2021 - mdpi.com
The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …

Recent advances in modulation of cardiovascular diseases by the gut microbiota

SK Masenga, B Hamooya, J Hangoma… - Journal of Human …, 2022 - nature.com
The gut microbiota has recently gained attention due to its association with cardiovascular
health, cancers, gastrointestinal disorders, and non-communicable diseases. One critical …