Multiple myeloma: Available therapies and causes of drug resistance
V Pinto, R Bergantim, HR Caires, H Seca… - Cancers, 2020 - mdpi.com
Multiple myeloma (MM) is the second most common blood cancer. Treatments for MM
include corticosteroids, alkylating agents, anthracyclines, proteasome inhibitors …
include corticosteroids, alkylating agents, anthracyclines, proteasome inhibitors …
The multiple myelomas—current concepts in cytogenetic classification and therapy
SK Kumar, SV Rajkumar - Nature reviews Clinical oncology, 2018 - nature.com
Multiple myeloma (MM) is a plasma cell neoplasm that accounts for 2% of all haematological
malignancies and predominantly affects older individuals (with a median age at diagnosis of …
malignancies and predominantly affects older individuals (with a median age at diagnosis of …
Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group
P Sonneveld, H Avet-Loiseau, S Lonial… - Blood, The Journal …, 2016 - ashpublications.org
Abstract The International Myeloma Working Group consensus updates the definition for
high-risk (HR) multiple myeloma based on cytogenetics Several cytogenetic abnormalities …
high-risk (HR) multiple myeloma based on cytogenetics Several cytogenetic abnormalities …
Multiple myeloma, version 3.2021, NCCN clinical practice guidelines in oncology
SK Kumar, NS Callander, K Adekola… - Journal of the National …, 2020 - jnccn.org
Multiple myeloma is a malignant neoplasm of plasma cells that accumulate in bone marrow,
leading to bone destruction and marrow failure. This manuscript discusses the management …
leading to bone destruction and marrow failure. This manuscript discusses the management …
Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus …
JR Mikhael, D Dingli, V Roy, CB Reeder, FK Buadi… - Mayo Clinic …, 2013 - Elsevier
Multiple myeloma remains an incurable neoplasm of plasma cells that affects more than
20,000 people annually in the United States. There has been a veritable revolution in this …
20,000 people annually in the United States. There has been a veritable revolution in this …
International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
Myeloma is a malignant proliferation of monoclonal plasma cells. Although morphologically
similar, several subtypes of the disease have been identified at the genetic and molecular …
similar, several subtypes of the disease have been identified at the genetic and molecular …
Development and validation of a cytogenetic prognostic index predicting survival in multiple myeloma
A Perrot, V Lauwers-Cances, E Tournay… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The wide heterogeneity in multiple myeloma (MM) outcome is driven mainly by
cytogenetic abnormalities. The current definition of high-risk profile is restrictive and …
cytogenetic abnormalities. The current definition of high-risk profile is restrictive and …
The molecular classification of multiple myeloma
F Zhan, Y Huang, S Colla, JP Stewart, I Hanamura… - Blood, 2006 - ashpublications.org
To better define the molecular basis of multiple myeloma (MM), we performed unsupervised
hierarchic clustering of mRNA expression profiles in CD138-enriched plasma cells from 414 …
hierarchic clustering of mRNA expression profiles in CD138-enriched plasma cells from 414 …
Cytogenetic abnormalities in multiple myeloma: association with disease characteristics and treatment response
Cytogenetic abnormalities are found in most multiple myeloma (MM) patients. Although their
prognostic value has been well studied, there are limited data on the association of primary …
prognostic value has been well studied, there are limited data on the association of primary …
Multiple myeloma, version 3.2017, NCCN clinical practice guidelines in oncology
SK Kumar, NS Callander, M Alsina… - Journal of the National …, 2017 - jnccn.org
Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These
neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone …
neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone …