Applications for pharmacogenomics in pharmacy practice: A scoping review

M Hayashi, DA Hamdy, SH Mahmoud - Research in Social and …, 2022 - Elsevier
Abstract Background Pharmacogenomics (PGx) can provide valuable pharmacokinetic and
pharmacodynamic information for the pharmacist's assessment of drug therapy, especially …

Utility of pharmacogenetic testing to optimise antidepressant pharmacotherapy in youth: a narrative literature review

B Roberts, Z Cooper, S Lu, S Stanley… - Frontiers in …, 2023 - frontiersin.org
Pharmacogenetics (PGx) is the study and application of how interindividual differences in
our genomes can influence drug responses. By evaluating individuals' genetic variability in …

Assessment of primary care practitioners' attitudes and interest in pharmacogenomic testing

DM Smith, T Namvar, RP Brown, TB Springfield… - …, 2020 - Taylor & Francis
Aims: Identify the attitudes and interests of primary care providers (PCPs) in applying clinical
pharmacogenomics (PGx) test results. Materials & methods: A questionnaire was designed …

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data

J Lanillos, M Carcajona, P Maietta, S Alvarez… - npj Genomic …, 2022 - nature.com
Exome sequencing is utilized in routine clinical genetic diagnosis. The technical robustness
of repurposing large-scale next-generation sequencing data for pharmacogenetics has …

Clinical importance of potential genetic determinants affecting propofol pharmacokinetics and pharmacodynamics

I Budic, T Jevtovic Stoimenov, D Pavlovic… - Frontiers in …, 2022 - frontiersin.org
Interindividual variability in response to drugs used in anesthesia has long been considered
the rule, not the exception. It is important to mention that in anesthesiology, the variability in …

Pharmacogenetics in psychiatric care, a call for uptake of available applications

CATC Lunenburg, C Gasse - Psychiatry Research, 2020 - Elsevier
In this narrative, we evaluate the role of pharmacogenetics in psychiatry from a pragmatic
clinical perspective and address current barriers of clinical implementation of …

Current published evidence on barriers and proposed strategies for genetic testing implementation in health care settings: a scoping review

SM Fahim, CSW Alexander, J Qian… - Journal of the American …, 2023 - Elsevier
Background The slow uptake of genetic testing in routine clinical practice warrants the
attention of researchers and practitioners to find effective strategies to facilitate …

Retrospective review of pharmacogenetic testing at an academic children's hospital

TA Roberts, JA Wagner, T Sandritter… - Clinical and …, 2021 - Wiley Online Library
There is limited evidence to support pharmacogenetic (PGx) testing in children. We
conducted a retrospective review of PGx testing among 452 patients at an academic …

Determining the potential clinical value of panel-based pharmacogenetic testing in patients with chronic pain or gastroesophageal reflux disease

AL Elchynski, EJ Cicali, MC Ferrer del Busto… - The …, 2021 - nature.com
We aimed to determine the potential value of panel-based pharmacogenetic (PGx) testing in
patients with chronic pain or gastroesophageal reflux disease (GERD) who underwent …

Projected Utility of Pharmacogenomic Testing Among Individuals Hospitalized with COVID‐19: A Retrospective Multicenter Study in the United States

JM Stevenson, GC Alexander… - Clinical and …, 2021 - Wiley Online Library
Many academic institutions are collecting blood samples from patients seeking treatment for
coronavirus disease 2019 (COVID‐19) to build research biorepositories. It may be feasible …