[HTML][HTML] Nasopharyngeal carcinoma ecology theory: Cancer as multidimensional spatiotemporal “unity of ecology and evolution” pathological ecosystem

W Luo - Theranostics, 2023 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a particular entity of head neck cancer that is generally
regarded as a genetic disease with diverse intertumor and intratumor heterogeneity. This …

Exosomes and organ-specific metastasis

L Zhao, X Ma, J Yu - Molecular therapy Methods & clinical development, 2021 - cell.com
The transmission of information between tumor cells and other cell types in the tumor
microenvironment plays an important role in tumor metastasis and is critically modulated by …

Biophysical, molecular and proteomic profiling of human retinal organoid-derived exosomes

P Arthur, S Kandoi, L Sun, A Kalvala, S Kutlehria… - Pharmaceutical …, 2023 - Springer
Purpose There is a growing interest in extracellular vesicles (EVs) for ocular applications as
therapeutics, biomarkers, and drug delivery vehicles. EVs secreted from mesenchymal stem …

Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: Involvement of GADD45α, integrin-α5,-β5,-β1, and autophagy

SK Surapaneni, N Patel, L Sun, N Kommineni… - Drug delivery and …, 2022 - Springer
To date, promising therapy for triple negative breast cancer (TNBC) remains a serious
concern clinically because of poor prognosis, resistance, and recurrence. Herein, anti …

Pathogenesis and therapeutic implications of EBV-associated epithelial cancers

YH Low, CJL Loh, DYY Peh, AJM Chu, S Han… - Frontiers in …, 2023 - frontiersin.org
Epstein-Barr virus (EBV), one of the most common human viruses, has been associated with
both lymphoid and epithelial cancers. Undifferentiated nasopharyngeal carcinoma (NPC) …

Natural killer cell phenotype and functionality affected by exposure to extracellular survivin and lymphoma-derived exosomes

HR Ferguson Bennit, A Gonda, J Kabagwira… - International Journal of …, 2021 - mdpi.com
The inherent abilities of natural killer (NK) cells to recognize and kill target cells place them
among the first cells with the ability to recognize and destroy infected or transformed cells …

Extracellular vesicles as a means of viral immune evasion, CNS invasion, and glia-induced neurodegeneration

MD Horn, AG MacLean - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Extracellular vesicles (EVs) are small, membrane-bound vesicles released by cells as a
means of intercellular communication. EVs transfer proteins, nucleic acids, and other …

Nanotechnology Frontiers in γ-herpesviruses treatments

M Granato - International Journal of Molecular Sciences, 2021 - mdpi.com
Epstein–Barr Virus (EBV) and Kaposi's sarcoma associated-herpesvirus (KSHV) are γ-
herpesviruses that belong to the Herpesviridae family. EBV infections are linked to the onset …

[HTML][HTML] Oncoviral Infections and Small Extracellular Vesicles

Ł Ważny, TL Whiteside, M Pietrowska - Viruses, 2024 - mdpi.com
Small extracellular vesicles (sEV) are small membrane-bound nanovesicles with a size
range below 200 nm that are released by all types of cells. sEV carry a diverse cargo of …

[HTML][HTML] Ceramide-dependent trafficking of Epstein-Barr virus LMP1 to small extracellular vesicles

SB York, SN Hurwitz, X Liu, DG Meckes Jr - Virology, 2023 - Elsevier
Epstein-Barr virus (EBV) is a human herpesvirus that is associated with a multitude of
cancers. The primary EBV oncogene latent membrane protein 1 (LMP1) is secreted from …