Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review

J Zhang, J Wu, F Liu, L Tong, Z Chen, J Chen… - European journal of …, 2019 - Elsevier
Anthocyanins, a class of water soluble flavonoids extracted from plants like berries and
soybean seed, have been shown to display obvious anti-oxidative, anti-inflammatory, and …

[HTML][HTML] Emerging gene and small molecule therapies for the neurodevelopmental disorder angelman syndrome

NA Copping, SM McTighe, KD Fink, JL Silverman - Neurotherapeutics, 2021 - Elsevier
Angelman syndrome (AS) is a rare (~ 1: 15,000) neurodevelopmental disorder characterized
by severe developmental delay and intellectual disability, impaired communication skills …

Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord

LM Milich, JS Choi, C Ryan, SR Cerqueira… - Journal of Experimental …, 2021 - rupress.org
The wound healing process that occurs after spinal cord injury is critical for maintaining
tissue homeostasis and limiting tissue damage, but eventually results in a scar-like …

Graphene quantum dots conjugated neuroprotective peptide improve learning and memory capability

S Xiao, D Zhou, P Luan, B Gu, L Feng, S Fan, W Liao… - Biomaterials, 2016 - Elsevier
Alzheimer disease (AD) is a neurodegenerative disorder and the most common form of
dementia. Histopathologically is characterized by the presence extracellular neuritic plaques …

Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin …

D Fan, Y Alamri, K Liu, M MacAskill, P Harris… - Nutrients, 2018 - mdpi.com
Background: Insulin-like growth factor-1 (IGF-1) function is impaired in Parkinson disease.
Cyclic glycine-proline (cGP), a metabolite of IGF-1, is neuroprotective through improving IGF …

Concise overview of glypromate neuropeptide research: from chemistry to pharmacological applications in neurosciences

SC Silva-Reis, IE Sampaio-Dias… - ACS Chemical …, 2023 - ACS Publications
Neurodegenerative diseases of the central nervous system (CNS) pose a serious health
concern worldwide, with a particular incidence in developed countries as a result of life …

Effects of IGF-1 on the cardiovascular system

M Obradovic, S Zafirovic, S Soskic… - Current …, 2019 - ingentaconnect.com
Cardiovascular (CV) diseases are the most common health problems worldwide, with a
permanent increase in incidence. Growing evidence underlines that insulin-like growth …

Proline‐containing peptides—New insight and implications: A Review

M Misiura, W Miltyk - Biofactors, 2019 - Wiley Online Library
The family of regulatory proline‐containing peptides (PCPs), also known as glyprolines,
exhibit significant biological activity. The group of glyprolines includes Gly‐Pro (GP), Pro‐Gly …

Cyclic glycine-proline (cGP) normalises insulin-like growth factor-1 (IGF-1) function: Clinical significance in the ageing brain and in age-related neurological conditions

J Guan, F Li, D Kang, T Anderson, T Pitcher… - Molecules, 2023 - mdpi.com
Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain
ageing and the progression of age-related neurological conditions. The reversible binding of …

Sevoflurane exposure may cause dysplasia of dendritic spines and result in fine motor dysfunction in developing mouse through the PI3K/AKT/mTOR pathway

L Zhong, X Ma, Y Niu, L Zhang, Z Xue, J Yan… - Frontiers in …, 2022 - frontiersin.org
Sevoflurane has become one of the most widely used volatile anesthetics in pediatric
surgery. However, sevoflurane exposure may interfere with dendritic development and …