Background: Alzheimer's (AD) and Parkinson's diseases (PD) show deposits of improperly
folded modified proteins. Protein expression mechanisms are involved since the early …

Alzheimer's disease (AD) may affect in excess of 90% of individuals with Down syndrome
(DS) after age 60, due to duplication of the APP gene in trisomy of chromosome 21, with …

The accumulation of endogenous formaldehyde is considered a pathogenic factor in
Alzheimer's Disease (AD). The purpose of this study was to investigate the relationship …

Background: Oligomeric amyloid-ß (Aß) is one of the major contributors to the
pathomechanism of Alzheimer's disease (AD); Aß oligomerization in plasma can be …

Global incidence of neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD)
and Parkinson's disease (PD) is rapidly increasing, but the diagnosis of these diseases at …

Urine-based formaldehyde has been reported to be a potential biomarker for Alzheimer's
disease (AD). However, there is a lack of research about the correlation between urine …

Alzheimer's disease (AD) is an incurable age-associated neurodegenerative disorder that is
characterized by irreversible progressive cognitive deficits and extensive brain damage. The …

Increased levels of Alzheimer-associated neuronal thread protein (AD7c-NTP) are often
detected in urine in the early course of Alzheimer's disease (AD), which makes it a promising …

Background Alzheimer's disease is a prevalent disease with a heavy global burden.
Proteomics is the systematic study of proteins and peptides to provide comprehensive …

This review highlights current developments, challenges, and future directions for the use of
invasive and noninvasive biosample-based small biosensors for early diagnosis of …