Myelin basic protein (MBP) is an abundant protein in central nervous system (CNS) myelin.
MBP has long been studied as a factor in the pathogenesis of the autoimmune …

Proteins are the major component of the living cell. They play crucial roles in the
maintenance of life, and their dysfunctions are known to cause different pathologies. One of …

The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …

This is a sequel to the previous Perspective “The CH–π hydrogen bond in chemistry.
Conformation, supramolecules, optical resolution and interactions involving carbohydrates” …

A typical casein micelle contains thousands of casein molecules, most of which form
thermodynamically stable complexes with nanoclusters of amorphous calcium phosphate …

Organic chemists tend to consider the conformation of compounds as a consequence of
repulsive steric interactions. In other words,“the steric effect” means “repulsive” in many …

The proposal that coupled folding to binding is not an obligatory mechanism for intrinsically
disordered (ID) proteins was put forward 10 years ago. The notion of fuzziness implies that …

Intrinsically disordered proteins (IDPs) are widespread in eukaryotic proteomes and
challenge the classical structure-function paradigm that equates a folded 3-D structure with …

Central nervous system myelin is a dynamic entity arising from membrane processes
extended from oligodendrocytes, which form a tightly wrapped multilamellar structure …

Proteins are dynamic creatures. Intrinsically disordered proteins (IDPs) function as
multiplicity of structures and their activities can only be described by stochastic structure …