Antipsychotic and antiepileptic drugs in bipolar disorder: the importance of therapeutic drug monitoring

A Musenga, MA Saracino, G Sani… - Current medicinal …, 2009 - ingentaconnect.com
Bipolar disorder (BD) is a long-term illness with mood swings which are characterized by
recurrent episodes of mania/hypomania and depression, with variable interpolations of …

Preparation, characterization and evaluation of quetiapine fumarate solid lipid nanoparticles to improve the oral bioavailability

A Narala, K Veerabrahma - Journal of pharmaceutics, 2013 - Wiley Online Library
Quetiapine fumarate is an antipsychotic drug with poor oral bioavailability (9%) due to first‐
pass metabolism. Present work is an attempt to improve oral bioavailability of quetiapine …

Central composite optimization of glycerosomes for the enhanced oral bioavailability and brain delivery of quetiapine fumarate

RM Zaki, MM Alfadhel, MA Alossaimi, LA Elsawaf… - Pharmaceuticals, 2022 - mdpi.com
This study aimed to formulate and statistically optimize glycerosomal formulations of
Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery …

Solid lipid nanoparticles approach for lymphatic targeting through intraduodenal delivery of quetiapine fumarate

M Yasir, PK Gaur, D Puri, P Shehkar… - Current drug …, 2018 - ingentaconnect.com
Background: Lymphatic route is one of the prominent routes for improving the poor
bioavailability of the drugs which undergo extensive hepatic first pass metabolism …

Quetiapine Fumarate: A Review of Analytical Methods

A Hamsa… - Journal of …, 2023 - academic.oup.com
Atypical antipsychotics are newer second-generation antipsychotics with weak dopamine
type 2 blocking but potent 5-HT2 antagonistic activity. They are considered first-line …

A novel electrochemical sensor for assaying of antipsychotic drug quetiapine

B Nigović, J Spajić - Talanta, 2011 - Elsevier
A novel electrochemical sensor based on poly (2-hydroxy-5-[(4-sulfophenyl) azo] benzoic
acid) film modified glassy carbon electrode for fast and simple quantification of trace amount …

Overview on Development and Validation of Force degradation studies with Stability Indicating Methods.

K Chandramore, S Sonawane - … Biotechnology Research Asia, 2022 - biotech-asia.org
This article provides an overview on Development and Validation of Force degradation
study with Stability Indicating Methods (SIMs) for drug substances. Different stress conditions …

Pre-clinical investigation of the modulation of quetiapine plasma pharmacokinetics and tissues biodistribution by lipid-core nanocapsules

F Carreño, K Paese, CM Silva, SS Guterres… - … of Pharmaceutical and …, 2016 - Elsevier
This study aims to investigate the changes in plasma pharmacokinetics and liver and brain
distribution of quetiapine (QTP) due to its encapsulation into a polymeric nanocarrier. For …

Analysis of quetiapine in human plasma using fluorescence spectroscopy

IM Mostafa, MA Omar, DM Nagy, SM Derayea - Spectrochimica Acta Part A …, 2018 - Elsevier
A simple and sensitive spectrofluorimetric method has been development for the assurance
of quetiapine fumarate (QTF). The proposed method was utilized for measuring the …

[HTML][HTML] Development and validation of a stability indicating RP-UPLC method for determination of quetiapine in pharmaceutical dosage form

RK Trivedi, MC Patel - Scientia pharmaceutica, 2011 - ncbi.nlm.nih.gov
The present work reports a stability indicating reversed phase ultra performance liquid
chromatography (RP-UPLC) method for the quantitative determination of quetiapine in …