MYC dysregulation initiates a dynamic process of genomic instability that is linked to tumor
initiation. Early studies using MYC-carrying retroviruses showed that these viruses were …

The antibody gene mutator activation-induced cytidine deaminase (AID) promiscuously
damages oncogenes, leading to chromosomal translocations and tumorigenesis. Why …

The transcription factor MYC plays a pivotal role in regulating various cellular processes and
has been implicated in tumorigenesis across multiple cancer types. MYC has emerged as a …

The role of miRNAs and its regulatory mechanism in myopia are indeterminate. Our study
aimed to investigate potential myopia‐associated non‐coding RNAs and related molecules …

Breast cancer is the second leading cause of cancer death in women and the presence of
metastasis significantly decreases survival. MicroRNAs are involved in tumor progression …

Background: Therapeutic targeting of Rho-Associated, Coiled-Coil Containing Protein
Kinase (ROCK) signaling for tumor cells and tumor endothelium has shown efficacy in pre …

Abstract miRNA-mRNA interaction depends on multiple factors such as 3'UTR isoforms, the
cell and tissue-specific expression levels of RNA-binding proteins, the sequence context …

Many tumors are characterized by recurrent translocations between a tissue-specific gene
and a proto-oncogene. The juxtaposition of the Ig heavy chain gene and Myc in Burkitt's …

The gene balance hypothesis predicts that an imbalance in the dosage sensitive genes
affects the cascade of gene networks that may influence the fitness of individuals. The …

TAFURT-CARDONA, Yaliana et al. High frequency of chromosome aberrations observed in
lymphocytes in postmenopausal obese women. Biomédica [online]. 2012, vol. 32, n. 3, pp …