Nonhuman primates as models for the discovery and development of radiation countermeasures

VK Singh, AO Olabisi - Expert opinion on drug discovery, 2017 - Taylor & Francis
Introduction: Despite significant scientific advances over the past six decades toward the
development of safe and effective radiation countermeasures for humans using animal …

Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin

M Khiao In, KC Richardson, A Loewa… - Anatomia, histologia …, 2019 - Wiley Online Library
Because of the shortage of human skin for research purposes, porcine skin has been used
as a model of human skin. The aim of this study was to identify the region of German …

Determination of lethality curve for cobalt-60 gamma-radiation source in rhesus macaques using subject-based supportive care

VK Singh, OO Fatanmi, SY Wise… - Radiation …, 2022 - meridian.allenpress.com
Well-characterized and validated animal models are required for the development of
medical countermeasures (MCMs) for acute radiation syndrome to mitigate injury due to …

Regional variations in the histology of porcine skin

NJ Turner, D Pezzone, SF Badylak - Tissue Engineering Part C …, 2015 - liebertpub.com
Porcine skin is commonly used as a model for human skin injury and as a source material
for biologic scaffold materials. Although remarkable similarities between porcine and human …

[HTML][HTML] Metformin alleviates radiation-induced skin fibrosis via the downregulation of FOXO3

JM Kim, H Yoo, JY Kim, SH Oh, JW Kang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Radiation-induced skin fibrosis is a common side effect of clinical
radiotherapy. Our previous next-generation sequencing (NGS) study demonstrated the …

Effects of Radiation-Induced Skin Injury on Hyaluronan Degradation and Its Underlying Mechanisms

J Dong, B Ren, Y Tian, G Peng, H Zhai, Z Meng, R Gu… - Molecules, 2023 - mdpi.com
Radiation-induced skin injury (RISI) is a frequent and severe complication with a complex
pathogenesis that often occurs during radiation therapy, nuclear incidents, and nuclear war …

Robotic 3-D laser-guided approach for efficient cutting of porcine belly

Y Liu, C Guo, MJ Er - IEEE/ASME Transactions on Mechatronics, 2021 - ieeexplore.ieee.org
Using autonomous meat cutting robots to cut porcine belly is a productive and more hygienic
solution over traditional, labor-intensive meat cutting practices such as the transmission of …

Establishment and characterization of a radiation‐induced dermatitis rat model

X Sheng, Y Zhou, H Wang, Y Shen… - Journal of Cellular …, 2019 - Wiley Online Library
Radiation‐induced dermatitis is a common and serious side effect after radiotherapy.
Current clinical treatments cannot efficiently or fully prevent the occurrence of post …

Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model

X Liu, T Guo, Z Huang, S Chen, L Chen, C Li… - Journal of Materials …, 2024 - pubs.rsc.org
Background: radiation-induced skin injury (RISI) is a common complication of radiotherapy,
affecting 85–95% of patients. Current treatments lack sufficient evidence of efficacy …

A proof of principle experiment for microbeam radiation therapy at the Munich compact light source

AC Dombrowsky, K Burger, AK Porth, M Stein… - Radiation and …, 2020 - Springer
Microbeam radiation therapy (MRT), a preclinical form of spatially fractionated radiotherapy,
uses an array of microbeams of hard synchrotron X-ray radiation. Recently, compact …