Mathematical modelling to study the horizontal transfer of antimicrobial resistance genes in bacteria: current state of the field and recommendations

QJ Leclerc, JA Lindsay… - Journal of the royal …, 2019 - royalsocietypublishing.org
Antimicrobial resistance (AMR) is one of the greatest public health challenges we are
currently facing. To develop effective interventions against this, it is essential to understand …

[HTML][HTML] The ecology of plasmid-coded antibiotic resistance: a basic framework for experimental research and modeling

M Zwanzig - Computational and Structural Biotechnology Journal, 2021 - Elsevier
Many antibiotic resistance genes are associated with plasmids. The ecological success of
these mobile genetic elements within microbial communities depends on varying …

[HTML][HTML] Calibrating spatiotemporal models of microbial communities to microscopy data: A review

A Yip, J Smith-Roberge, SH Khorasani… - PLOS Computational …, 2022 - journals.plos.org
Spatiotemporal models that account for heterogeneity within microbial communities rely on
single-cell data for calibration and validation. Such data, commonly collected via microscopy …

Prevalence of colistin-resistant Escherichia coli harbouring mcr-1 in raw beef and ready-to-eat beef products in Egypt

RF Sabala, M Usui, Y Tamura, SM Abd-Elghany… - Food Control, 2021 - Elsevier
The emergence of antibiotic-resistant bacteria in food, mainly contaminated meat and its
products, and their transfer to humans is of great concern. To evaluate the potential risk of …

The conjugation window in an Escherichia coli K-12 strain with an IncFII plasmid

B Headd, SA Bradford - Applied and environmental microbiology, 2020 - Am Soc Microbiol
Many studies have examined the role that conjugation plays in disseminating antibiotic
resistance genes in bacteria. However, relatively little research has quantitively examined …

Temperature and soil moisture change microbial allocation of pesticide‐derived carbon

J Wirsching, LC Rodriguez, F Ditterich… - European Journal of …, 2023 - Wiley Online Library
Temperature and soil moisture are known to control pesticide mineralization. Half‐life times
(DT 50 DT _ 50) derived from pesticide mineralization curves generally indicate longer …

Gene-centric model approaches for accurate prediction of pesticide biodegradation in soils

L Chavez Rodriguez, B Ingalls, E Schwarz… - Environmental …, 2020 - ACS Publications
Pesticides are widely used in agriculture despite their negative impact on ecosystems and
human health. Biogeochemical modeling facilitates the mechanistic understanding of …

Tetrahymena promotes interactive transfer of carbapenemase gene encoded in plasmid between fecal Escherichia coli and environmental Aeromonas caviae

M Matsushita, T Okubo, T Hasegawa… - Microbiology and …, 2018 - Wiley Online Library
Tetrahymena can facilitate plasmid transfer among Escherichia coli or from E. coli to
Salmonella Enteritidis via vesicle accumulation. In this study, whether ciliates promote the …

[HTML][HTML] A streamlined approach for fluorescence labelling of low-copy-number plasmids for determination of conjugation frequency by flow cytometry

Q Qi, M Kamruzzaman, JR Iredell - Microorganisms, 2023 - mdpi.com
Bacterial conjugation plays a major role in the dissemination of antibiotic resistance and
virulence traits through horizontal transfer of plasmids. Robust measurement of conjugation …

Parameter Estimation of the Potassium Channel in the Hodgkin-Huxley Model

P Yue - 2024 - atrium.lib.uoguelph.ca
In this thesis, we constructed two methods, one using Differential Evolution (DE) and one
using a Feedforward Neural Network (FNN), to estimate the Potassium channel parameters …