[HTML][HTML] Heat-shock proteins in leukemia and lymphoma: multitargets for innovative therapeutic approaches

V Cabaud-Gibouin, M Durand, R Quéré, F Girodon… - Cancers, 2023 - mdpi.com
Simple Summary Heat-shock proteins (HSPs) are molecular chaperones overexpressed in
tumor cells and are necessary for their survival. In leukemia and lymphoma, HSPs have …

[HTML][HTML] Is It Still Possible to Think about HSP70 as a Therapeutic Target in Onco-Hematological Diseases?

N Mouawad, G Capasso, E Ruggeri, L Martinello… - Biomolecules, 2023 - mdpi.com
The search for molecules to be targeted that are involved in apoptosis resistance/increased
survival and pathogenesis of onco-hematological malignancies is ongoing since these …

Hsp27, Hsp60, Hsp70, or Hsp90 depletion enhances the antitumor effects of resveratrol via oxidative and ER stress response in human glioblastoma cells

EÖ Uçar, A Şengelen, EM Kamalı - Biochemical Pharmacology, 2023 - Elsevier
Therapeutic resistance of gliomas is still a crucial issue and closely related to induced heat
shock response (HSR). Resveratrol (RSV) is a promising experimental agent for …

Focal adhesion kinase activation by calcium‐dependent calpain is involved in chronic lymphocytic leukaemia cell aggressiveness

F Severin, N Mouawad, E Ruggeri… - British Journal of …, 2023 - Wiley Online Library
Signalling events downstream the B‐cell receptor (BCR) are central for the survival and
progression of chronic lymphocytic leukaemia (CLL) cells. Focal adhesion kinase (FAK) …

[HTML][HTML] Heat Shock Proteins, a Double-Edged Sword: Significance in Cancer Progression, Chemotherapy Resistance and Novel Therapeutic Perspectives

D Kunachowicz, M Król-Kulikowska, W Raczycka… - Cancers, 2024 - mdpi.com
Simple Summary Among the many mechanisms developed by cancer cells in order to
survive and sustain constant proliferation under stress conditions, a system based on heat …

Bacterial heat shock protein genes during induction chemotherapy in pediatric patients with acute lymphoblastic leukemia

KA Dunn, E MacDonald, T MacDonald… - Future Oncology, 2024 - Taylor & Francis
Background: Heat shock proteins (HSP) protect cancer cells. Gastrointestinal bacteria
contain HSP genes and can release extracellular vesicles which act as biological shuttles …

How receptor tyrosine kinase‐like orphan receptor 1 meets its partners in chronic lymphocytic leukemia

N Mouawad, E Ruggeri, G Capasso… - Hematological …, 2024 - Wiley Online Library
Chronic lymphocytic leukemia (CLL) is the most common leukemia in western societies,
recognized by clinical and molecular heterogeneity. Despite the success of targeted …

[PDF][PDF] VALIDAZIONE DI UN'ANALISI DI MEMBRANE-BASED ARRAY PER L'INDIVIDUAZIONE DI MARKER DI RESISTENZA AD IBRUTINIB NELLA LEUCEMIA …

R GALIAZZO - thesis.unipd.it
La leucemia linfatica cronica (LLC) è la forma più comune di leucemia dell'adulto ed è
caratterizzata dall'accumulo clonale di piccoli linfociti B CD19+/CD5+/CD23+ dovuto sia ad …