Animal speciation often involves novel behavioral features that rely on nervous system
evolution. Human-specific brain features have been proposed to underlie specialized …

Synapses of the neocortex specialized during human evolution to develop over extended
timescales, process vast amounts of information and increase connectivity, which is thought …

The enhanced cognitive abilities characterizing the human species result from specialized
features of neurons and circuits. Here, we report that the hominid-specific gene LRRC37B …

Fast-spiking interneurons (FSINs) provide fast inhibition that synchronizes neuronal activity
and is critical for cognitive function. Fast synchronization frequencies are evolutionary …

Cerebral cortex biopsies enable the investigation of native developing and mature human
brain tissue. Here, we present a protocol to process human cortical biopsies from the …

Long‐range thalamocortical communication is central to anesthesia‐induced loss of
consciousness and its reversal. However, isolating the specific neural networks connecting …

Aging is associated with the slowdown of neuronal processing and cognitive performance in
the brain; however, the exact cellular mechanisms behind this deterioration in humans are …

Vibration is an indispensable part of the tactile perception, which is encoded to oscillatory
synaptic currents by receptors and transferred to neurons in the brain. The A2 and B1 …

Information flow in the mammalian neocortex is shaped through canonical motifs of
connected excitatory pyramidal projection neurons and a diverse population of inhibitory …

While many core biological processes are conserved across species, the human brain has
evolved with unique capacities. Current understanding of the neurobiological mechanisms …