Role of internalin proteins in the pathogenesis of Listeria monocytogenes
Listeria monocytogenes is a food‐borne bacterium that causes gastroenteritis, meningitis, or
abortion. L. monocytogenes induces its internalization (entry) into human cells and either …
abortion. L. monocytogenes induces its internalization (entry) into human cells and either …
Listeria monocytogenes—How This Pathogen Uses Its Virulence Mechanisms to Infect the Hosts
J Osek, K Wieczorek - Pathogens, 2022 - mdpi.com
Listeriosis is a serious food-borne illness, especially in susceptible populations, including
children, pregnant women, and elderlies. The disease can occur in two forms: non-invasive …
children, pregnant women, and elderlies. The disease can occur in two forms: non-invasive …
Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts
Orofacial clefts (OFCs) represent a large fraction of human birth defects and are one of the
most common phenotypes affected by large copy number variants (CNVs). Due to the limited …
most common phenotypes affected by large copy number variants (CNVs). Due to the limited …
The Diaphanous-Related Formins Promote Protrusion Formation and Cell-to-Cell Spread of Listeria monocytogenes
R Fattouh, H Kwon, MA Czuczman… - The Journal of …, 2015 - academic.oup.com
Abstract The Gram-positive bacterium Listeria monocytogenes is a facultative intracellular
pathogen whose virulence depends on its ability to spread from cell to cell within an infected …
pathogen whose virulence depends on its ability to spread from cell to cell within an infected …
Metabolic adaptation of intracellular bacteria and fungi to macrophages
The mature phagosome of macrophages is a hostile environment for the vast majority of
phagocytosed microbes. In addition to active destruction of the engulfed microbes by …
phagocytosed microbes. In addition to active destruction of the engulfed microbes by …
CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection
Salmonella presents a global public health concern. Central to Salmonella pathogenicity is
an ability to subvert host defences through strategically targeting host proteins implicated in …
an ability to subvert host defences through strategically targeting host proteins implicated in …
Listeria monocytogenes co-opts the host exocyst complex to promote internalin A-mediated entry
The bacterial pathogen Listeria monocytogenes induces its internalization (entry) into
intestinal epithelial cells through interaction of its surface protein, internalin A (InlA), with the …
intestinal epithelial cells through interaction of its surface protein, internalin A (InlA), with the …
Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation
N Tegtmeyer, A Harrer, K Rottner, S Backert - Cancers, 2021 - mdpi.com
Simple Summary Various microbial pathogens target the actin-binding protein cortactin to
promote their own uptake, proliferation and spread, and exhibit proposed roles in human …
promote their own uptake, proliferation and spread, and exhibit proposed roles in human …
Interaction of microbial pathogens with host exocytic pathways
Many microbial pathogens co‐opt or perturb host membrane trafficking pathways. This
review covers recent examples in which microbes interact with host exocytosis, the fusion of …
review covers recent examples in which microbes interact with host exocytosis, the fusion of …
Listeria monocytogenes crosses blood brain barrier through Rho GTPases induced migration of macrophages and inflammatory interleukin expression
AD Shahid, Y Lu, MA Iqbal, L Lin, S Huang, X Jiang… - Microbial …, 2021 - Elsevier
Listeria monocytogenes crossing the blood-brain barrier in the form of “Trojan Horse” is of
great significance for the establishment of bacterial encephalitis and meningitis. Induction of …
great significance for the establishment of bacterial encephalitis and meningitis. Induction of …