Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

Reductions in blood flow to the brain of sufficient duration and extent lead to stroke, which
results in damage to neuronal networks and the impairment of sensation, movement or …

Spontaneous activity plays an important role in the function of neural circuits. Although many
similarities between spontaneous and sensory-evoked neocortical activity have been …

Electrophysiology, the'gold standard'for investigating neuronal signalling, is being
challenged by a new generation of optical probes. Together with new forms of microscopy …

The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined
system for exploring the link between molecular mechanisms, synaptic circuits, and …

Tactile information is actively acquired and processed in the brain through concerted
interactions between movement and sensation. Somatosensory input is often the result of …

Systems-level organization in spontaneous infra-slow (< 0.1 Hz) brain activity, measured
using blood oxygen signals in fMRI and optical imaging, has become a major theme in the …

Resting-state functional connectivity (FC), which measures the correlation of spontaneous
hemodynamic signals (HemoS) between brain areas, is widely used to study brain networks …

The primary somatosensory barrel cortex processes tactile vibrissae information, allowing
rodents to actively perceive spatial and textural features of their immediate surroundings …

In cerebral cortex, ongoing activity absent a stimulus can resemble stimulus-driven activity in
size and structure. In particular, spontaneous activity in cat primary visual cortex (V1) has …