Squaramides as bioisosteres in contemporary drug design

KA Agnew-Francis, CM Williams - Chemical Reviews, 2020 - ACS Publications
Squaramides represent a class of vinylogous amides that are derived from the squarate
oxocarbon dianion. While they have been known since the 1950s, squaramides have only …

Discovery of a novel amino lipid that improves lipid nanoparticle performance through specific interactions with mRNA

M Cornebise, E Narayanan, Y Xia… - Advanced Functional …, 2022 - Wiley Online Library
Lipid nanoparticles (LNPs) are capable of delivering messenger ribonucleic acid (mRNA)
efficiently and systemically as a result of both particle composition and architecture. The …

Aromatic gain in a supramolecular polymer

V Saez Talens, P Englebienne, TT Trinh… - Angewandte Chemie …, 2015 - Wiley Online Library
The synergy of aromatic gain and hydrogen bonding in a supramolecular polymer is
explored. Partially aromatic bis (squaramide) bolaamphiphiles were designed to self …

Influence of the Z/E Isomerism on the Pathway Complexity of a Squaramide‐Based Macrocycle

F Orvay, J Cerdá, C Rotger, E Orti, J Arago, A Costa… - Small, 2021 - Wiley Online Library
The rising interest on pathway complexity in supramolecular polymerization has prompted
the finding of novel monomer designs able to stabilize kinetically trapped species and …

Self-assembled fibrillar networks of a multifaceted chiral squaramide: supramolecular multistimuli-responsive alcogels

J Schiller, JV Alegre-Requena, E Marqués-López… - Soft Matter, 2016 - pubs.rsc.org
Chiral N, N′-disubstituted squaramide 1 has been found to undergo self-assembly in a
variety of alcoholic solvents at low concentrations leading to the formation of novel …

A theoretical insight into non-covalent supramolecular interactions in the solid state structures of two octahedral iron (iii) complexes

T Basak, A Frontera, S Chattopadhyay - CrystEngComm, 2020 - pubs.rsc.org
The nature and characteristics of the C–H⋯ π interactions that play an important role in
crystal packing of two iron (III) complexes have been discussed.[Fe (HL1) 2 (NCSe) 2] Cl (1) …

Exploration of tertiary aminosquaramide bifunctional organocatalyst in controlled/living ring‐opening polymerization of l‐lactide

A Rostami, E Sadeh, S Ahmadi - Journal of Polymer Science …, 2017 - Wiley Online Library
ABSTRACT A series of tertiary aminosquaramides as bifunctional organocatalysts in the ring‐
opening polymerization (ROP) of l‐lactide (l‐LA) were developed, allowing the activation of …

Self-assembling of zwitterionic squaramides through electrostatically compressed face-to-face π-stacking: a new supramolecular synthon

A Portell, M Font-Bardia, R Prohens - Crystal growth & design, 2013 - ACS Publications
We report, herein, a novel supramolecular synthon based on the electrostatic compression
phenomenon. A zwitterionic squaric acid/squaramide compound serves as a model for the …

Thioureas and Squaramides: Comparison with Ureas as Assembly Directing Motifs for m-Xylene Macrocycles

AJ Sindt, MD Smith, PJ Pellechia… - Crystal Growth & …, 2018 - ACS Publications
Intentional design of crystalline frameworks requires a good understanding of how inter-and
intramolecular forces act together to afford solid-state structures. Herein, we synthesize and …

A systematic approach to identify cooperatively bound homotrimers

J Yang, MP Waller - The Journal of Physical Chemistry A, 2013 - ACS Publications
A systematic multistage computational procedure is presented to investigate cooperativity
within trimeric molecular complexes. It is an alternative to exhaustive or stochastic-based …