Advances in bioresorbable triboelectric nanogenerators

M Kang, DM Lee, I Hyun, N Rubab, SH Kim… - Chemical …, 2023 - ACS Publications
With the growing demand for next-generation health care, the integration of electronic
components into implantable medical devices (IMDs) has become a vital factor in achieving …

Single administration vaccines: delivery challenges, in vivo performance, and translational considerations

K Michaelides, M Prasanna, R Badhan… - Expert Review of …, 2023 - Taylor & Francis
Introduction With a limited global supply of vaccines and an increasing vaccine hesitancy,
improving vaccination coverage has become a priority. Current vaccination regimes require …

In vitro degradation of 3D-printed poly (L-lactide-Co-glycolic acid) scaffolds for tissue engineering applications

A Ghosh Dastidar, SA Clarke, E Larrañeta, F Buchanan… - Polymers, 2023 - mdpi.com
The creation of scaffolds for cartilage tissue engineering has faced significant challenges in
developing constructs that can provide sufficient biomechanical support and offer suitable …

A long-acting formulation of rifabutin is effective for prevention and treatment of Mycobacterium tuberculosis

M Kim, CE Johnson, AA Schmalstig, A Annis… - Nature …, 2022 - nature.com
Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis (Mtb)
and is a major cause of morbidity and mortality. Successful treatment requires strict …

Characterizing release mechanisms of leuprolide acetate-loaded PLGA microspheres for IVIVC development I: in vitro evaluation

K Hirota, AC Doty, R Ackermann, J Zhou… - Journal of controlled …, 2016 - Elsevier
Release testing of parental controlled release microspheres is an essential step in
controlling quality and predicting the duration of efficacy. In the first of a two-part study, we …

Poly(lactic-co-glycolic acid) Nanoparticles for the Encapsulation and Gastrointestinal Release of Vitamin B9 and Vitamin B12

MJ Ramalho, JA Loureiro… - ACS Applied Nano …, 2021 - ACS Publications
Deficiencies of vitamin B9 (VB9) and vitamin B12 (VB12) are very common among aged
adults due to their poor oral bioavailability. However, the poor stability of these vitamins …

Preparation, characterization, and enhanced antimicrobial activity: quercetin-loaded PLGA nanoparticles against foodborne pathogens

T ARASOĞLU, S Derman… - Turkish Journal of …, 2017 - journals.tubitak.gov.tr
The use of quercetin as a bioflavonoid is becoming increasingly common in food industries
even though poor water solubility, instability, absorption, and permeability have limited its …

Paclitaxel delivery system based on poly (lactide-co-glycolide) microparticles and chitosan thermo-sensitive gel for mammary adenocarcinoma treatment

JI Pesoa, MJ Rico, VR Rozados… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives To evaluate the combination of more than one release system in the same
formulation as a useful strategy to achieve paclitaxel delivery in a more sustained and …

Kinetic degradation and biocompatibility evaluation of polycaprolactone‐based biologics delivery matrices for regenerative engineering of the rotator cuff

A Prabhath, VN Vernekar, V Vasu… - … Research Part A, 2021 - Wiley Online Library
Whereas synthetic biodegradable polymers have been successfully applied for the delivery
of biologics in other tissues, the anatomical complexity, poor blood supply, and reduced …

Biodegradation study of PLGA as an injectable in situ depot-forming implant for controlled release of paclitaxel

MS Amini-Fazl - Polymer Bulletin, 2021 - Springer
In this study, poly (d, l-lactide-co-glycolide), PLGA, was developed as an in situ forming
implants (ISFIs) to improve the therapeutic efficiency and to devoid the adverse effects of the …