Optic neuritis

AT Toosy, DF Mason, DH Miller - The Lancet Neurology, 2014 - thelancet.com
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Neuromyelitis optica: clinical features, immunopathogenesis and treatment

S Jarius, B Wildemann, F Paul - Clinical & Experimental …, 2014 - academic.oup.com
Summary The term 'neuromyelitis optica'('Devic's syndrome', NMO) refers to a syndrome
characterized by optic neuritis and myelitis. In recent years, the condition has raised …

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients

S Jarius, K Ruprecht, B Wildemann, T Kuempfel… - Journal of …, 2012 - Springer
Background The diagnostic and pathophysiological relevance of antibodies to aquaporin-4
(AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been …

Prognostic factors and disease course in aquaporin-4 antibody-positive patients with neuromyelitis optica spectrum disorder from the United Kingdom and Japan

J Kitley, MI Leite, I Nakashima, P Waters, B McNeillis… - Brain, 2012 - academic.oup.com
Neuromyelitis optica and neuromyelitis optica spectrum disorders have been recently
associated with the disease-specific autoantibody aquaporin-4, thought to be pathogenic …

Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype

J Kitley, M Woodhall, P Waters, MI Leite, E Devenney… - Neurology, 2012 - AAN Enterprises
Objectives: To report an association of myelin-oligodendrocyte glycoprotein (MOG)
antibodies with aquaporin-4 (AQP4) antibody–seronegative neuromyelitis optica (NMO) and …

The history of neuromyelitis optica

S Jarius, B Wildemann - Journal of neuroinflammation, 2013 - Springer
The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of
patients in 2004 has revived interest in neuromyelitis optica (NMO). While the history of …

Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica

Y Jiao, JP Fryer, VA Lennon, SM Jenkins, AML Quek… - Neurology, 2013 - AAN Enterprises
Objective: To 1) determine, using contemporary recombinant antigen–based assays, the
aquaporin-4 (AQP4)–immunoglobulin G (IgG) detection rate in sequential sera of patients …

[HTML][HTML] Multiple sclerosis: diagnosis and differential diagnosis

S Ömerhoca, SY Akkaş, NK İçen - Archives of Neuropsychiatry, 2018 - ncbi.nlm.nih.gov
The diagnostic criteria for multiple sclerosis (MS) have been continuously evolved since
1950's, and gained speed parallel to the development of detailed laboratory methods. The …

Aquaporin-4 antibody–negative neuromyelitis optica: distinct assay sensitivity–dependent entity

R Marignier, R Bernard-Valnet, P Giraudon… - Neurology, 2013 - AAN Enterprises
Objective: To optimize aquaporin-4 (AQP4) antibody (Ab) detection and to assess the
influence of the increased sensitivity of the assay on the demographic and disease-related …

Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain

S Saadoun, P Waters, GP Owens, JL Bennett… - Acta neuropathologica …, 2014 - Springer
Introduction Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) are present
in some neuromyelitis optica patients who lack antibodies against aquaporin-4 (AQP4-IgG) …