Chlamydia trachomatis: the persistent pathogen

SS Witkin, E Minis, A Athanasiou, J Leizer… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium whose only natural host is
humans. Although presenting as asymptomatic in most women, genital tract chlamydial …

Pathogenesis of Genital Tract Disease Due to Chlamydia trachomatis

T Darville, TJ Hiltke - The Journal of infectious diseases, 2010 - academic.oup.com
Although the pathologic consequences of C. trachomatis genital infection are well-
established, themechanism (s) that result in chlamydia-induced tissue damage are not fully …

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

G Stary, A Olive, AF Radovic-Moreno, D Gondek… - Science, 2015 - science.org
INTRODUCTION Administering vaccines through nonmucosal routes often leads to poor
protection against mucosal pathogens, presumably because such vaccines do not generate …

[HTML][HTML] Chlamydiaceae: Diseases in Primary Hosts and Zoonosis

HC Cheong, CYQ Lee, YY Cheok, GMY Tan, CY Looi… - Microorganisms, 2019 - mdpi.com
Bacteria of the Chlamydiaceae family are a type of Gram-negative microorganism typified by
their obligate intracellular lifestyle. The majority of the members in the Chlamydiaceae family …

The Structure of the Human Vaginal Stratum Corneum and its Role in Immune Defense

DJ Anderson, J Marathe… - American journal of …, 2014 - Wiley Online Library
The superficial layers of the human vaginal epithelium, which form an interface between
host and environment, are comprised of dead flattened cells that have undergone a terminal …

[HTML][HTML] Infections and pregnancy: effects on maternal and child health

M Kumar, M Saadaoui, S Al Khodor - Frontiers in Cellular and …, 2022 - frontiersin.org
Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

Epidemiology of Chlamydia trachomatis infection in women and the cost-effectiveness of screening

JA Land, J Van Bergen, SA Morre… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND The majority of Chlamydia trachomatis infections in women are
asymptomatic, but may give rise to pelvic inflammatory disease (PID) and tubal infertility …

Human and pathogen factors associated with Chlamydia trachomatis-related infertility in women

S Menon, P Timms, JA Allan, K Alexander… - Clinical microbiology …, 2015 - Am Soc Microbiol
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen
worldwide. Infection can result in serious reproductive pathologies, including pelvic …

[HTML][HTML] Seventy years of Chlamydia vaccine research–limitations of the past and directions for the future

S Phillips, BL Quigley, P Timms - Frontiers in microbiology, 2019 - frontiersin.org
Chlamydia is a major bacterial pathogen that infects humans, as well as a wide range of
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …

[PDF][PDF] Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response

C Chumduri, RK Gurumurthy, PK Zadora, Y Mi… - Cell host & …, 2013 - cell.com
The obligate intracellular bacterial pathogen Chlamydia trachomatis (Ctr) has been
associated with cervical and ovarian cancer development. However, establishment of …