Nanomaterials for T-cell cancer immunotherapy

N Gong, NC Sheppard, MM Billingsley, CH June… - Nature …, 2021 - nature.com
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …

Cancer nanomedicine for combination cancer immunotherapy

J Nam, S Son, KS Park, W Zou, LD Shea… - Nature Reviews …, 2019 - nature.com
Cancer immunotherapy is revolutionizing oncology. However, dose-limiting toxicities and
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …

Using immunotherapy to boost the abscopal effect

W Ngwa, OC Irabor, JD Schoenfeld, J Hesser… - Nature Reviews …, 2018 - nature.com
More than 60 years ago, the effect whereby radiotherapy at one site may lead to regression
of metastatic cancer at distant sites that are not irradiated was described and called the …

THz medical imaging: from in vitro to in vivo

Z Yan, LG Zhu, K Meng, W Huang, Q Shi - Trends in Biotechnology, 2022 - cell.com
Terahertz (THz) radiation has attracted considerable attention in medical imaging owing to
its nonionizing and spectral fingerprinting characteristics. To date, most studies have …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Nanoparticles in biomedical applications

K McNamara, SAM Tofail - Advances in Physics: X, 2017 - Taylor & Francis
Nanoparticles are defined as solid colloidal particles ranging in size from 10 to 1000 nm.
Nanoparticles offer many benefits to larger particles such as increased surface-to-volume …

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

[HTML][HTML] Various methods of gold nanoparticles (GNPs) conjugation to antibodies

MH Jazayeri, H Amani, AA Pourfatollah… - Sensing and bio …, 2016 - Elsevier
The unique properties of gold nanoparticles, their rich surface chemistry, and low toxicity as
well as easy methods of synthesis have promoted conjugation of the particles with …

Recent advances in subcellular targeted cancer therapy based on functional materials

WH Chen, GF Luo, XZ Zhang - Advanced Materials, 2019 - Wiley Online Library
Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

In Vivo Neuroimaging of Exosomes Using Gold Nanoparticles

O Betzer, N Perets, A Angel, M Motiei, T Sadan… - ACS …, 2017 - ACS Publications
Exosomes are emerging as effective therapeutic tools for various pathologies. These
extracellular vesicles can bypass biological barriers, including the blood-brain barrier, and …