Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Significantly, much of the activity of Citrus flavonoids appears to impact blood and
microvascular endothelial cells, and it is not surprising that the two main areas of research …

Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

Severe hemolysis or myolysis occurring during pathological states, such as sickle cell
disease, ischemia reperfusion, and malaria results in high levels of free heme, causing …

Abstract Interleukin (IL)-8, a prototypic human chemokine, was detected more than a decade
ago as the founding member of the chemokine superfamily. One of the most remarkable …

Cytokines play a very important role in nearly all aspects of inflammation and immunity. The
term'interleukin'(IL) has been used to describe a group of cytokines with complex …

Angiogenesis is essential for tumor growth, metastasis, arteriosclerosis as well as embryonic
development and wound healing. Its process is dependent on cell proliferation, migration …

Abstract Interleukin-8 (IL-8, or CXCL8), which is a chemokine with a defining CXC amino
acid motif that was initially characterized for its leukocyte chemotactic activity, is now known …

The aggressive nature of metastatic human cancer has been shown to be related to
numerous abnormalities in growth factors and their receptors. These perturbations confer a …