Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

The damage inflicted on the myocardium during acute myocardial infarction is the result of 2
processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the …

Age‐related macular degeneration (AMD) is a progressive degenerative disease that is the
leading cause of vision loss in the elderly population. Degeneration/dysregulation of the …

Nucleosomal fragmentation of DNA is a hallmark of apoptosis (programmed cell death), and
results from the activation of nucleases in cells undergoing apoptosis. One such nuclease …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
the elderly. The underlying mechanism of non-neovascular AMD (dry AMD), also named …

In humans and experimental models of renal ischemia, tubular cells in various nephron
segments undergo necrotic and/or apoptotic cell death. Various factors, including nucleotide …

Photodynamic therapy (PDT) for cancer treatment has drawn increased attention over the
last decades. Herein, we introduce a novel family of low-molecular-weight coumarins as …

Studies have emphasized an antineoplastic effect of the non-psychoactive, phyto-
cannabinoid, Cannabidiol (CBD). However, the molecular mechanism underlying its …

Cellular energy homeostasis is a fundamental process that governs the overall health of the
cell and is paramount to cell survival. Central to this is the control of ATP generation and …

Topoisomerase inhibitors are among the most efficient inducers of apoptosis. The main
pathways leading from topoisomerase-mediated DNA damage to cell death involve …