[HTML][HTML] Therapeutic options for management of endometrial hyperplasia
V Chandra, JJ Kim, DM Benbrook… - Journal of …, 2016 - synapse.koreamed.org
Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging
from a slightly disordered pattern that exaggerates the alterations seen in the late …
from a slightly disordered pattern that exaggerates the alterations seen in the late …
Targeting Wnt signaling in endometrial cancer
Simple Summary Wnt has diverse regulatory roles at multiple cellular levels and numerous
targeting points, and aberrant Wnt signaling has crucial roles in carcinogenesis, metastasis …
targeting points, and aberrant Wnt signaling has crucial roles in carcinogenesis, metastasis …
[HTML][HTML] Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis
Colorectal cancer (CRC) is a leading cause of the cancer-related deaths worldwide. Thus,
developing novel and targeted therapies for inhibiting CRC progression and metastasis is …
developing novel and targeted therapies for inhibiting CRC progression and metastasis is …
Design and synthesis of ERα/ERβ selective coumarin and chromene derivatives as potential anti-breast cancer and anti-osteoporotic agents
Several new coumarin and chromene prototype derivatives have been synthesised and
evaluated for their ERα and ERβ selective activity. Coumarin prototype compounds 18 & 19 …
evaluated for their ERα and ERβ selective activity. Coumarin prototype compounds 18 & 19 …
Tandem Alkyne Hydroacylation and Oxo-Michael Addition: Diastereoselective Synthesis of 2, 3-Disubstituted Chroman-4-ones and Fluorinated Derivatives
XW Du, LM Stanley - Organic letters, 2015 - ACS Publications
Tandem reactions involving Rh-catalyzed intermolecular hydroacylations of alkynes with
salicylaldehydes followed by intramolecular oxo-Michael additions are described for the …
salicylaldehydes followed by intramolecular oxo-Michael additions are described for the …
(−)-Epigallocatechin-3-gallate induces apoptosis in human endometrial adenocarcinoma cells via ROS generation and p38 MAP kinase activation
(−)-Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea, has been shown
to inhibit carcinogenesis of various tumor types. The aim of this study was to elucidate the …
to inhibit carcinogenesis of various tumor types. The aim of this study was to elucidate the …
Inhibitory effect of 2-(piperidinoethoxyphenyl)-3-(4-hydroxyphenyl)-2H-benzo (b) pyran (K-1) on human primary endometrial hyperplasial cells mediated via combined …
Endometrial hyperplasia is a precursor to the most common gynecologic cancer diagnosed
in women. Apart from estrogenic induction, aberrant activation of the Wnt/β-catenin signal is …
in women. Apart from estrogenic induction, aberrant activation of the Wnt/β-catenin signal is …
Synthesis of targeted dibenzo [b, f] thiepines and dibenzo [b, f] oxepines as potential lead molecules with promising anti-breast cancer activity
A targeted library of substituted dibenzo [b, f] thiepines and dibenzo [b, f] oxepines
(prototypes I, II and III), and structurally analogous to tamoxifen have been synthesized as a …
(prototypes I, II and III), and structurally analogous to tamoxifen have been synthesized as a …
[HTML][HTML] Paeoniflorin inhibits proliferation of endometrial cancer cells via activating MAPK and NF‑κB signaling pathways
J Zhang, F Wang, H Wang… - Experimental and …, 2017 - spandidos-publications.com
Paeoniflorin (PAE), a principal bioactive component of Paeonia lactiflora Pall., appears to
have antitumor properties. However, the pharmacological activity of PAE in endometrial …
have antitumor properties. However, the pharmacological activity of PAE in endometrial …
Antiproliferative and apoptotic activities of triterpenoid saponins from the roots of Platycodon grandiflorum and their structure-activity relationships
The present study was undertaken to investigate the antiproliferative and apoptotic activities
of Platycodon saponins, including platycodin D, 2′′-O-acetylplatycodin D, 3′′-O …
of Platycodon saponins, including platycodin D, 2′′-O-acetylplatycodin D, 3′′-O …