Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline–Update 2022

ML Gauci, C Aristei, JC Becker, A Blom… - European Journal of …, 2022 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all
cutaneous malignancies. It is found predominantly in white populations and risk factors …

Merkel cell carcinoma

JC Becker, A Stang, JA DeCaprio, L Cerroni… - Nature reviews Disease …, 2017 - nature.com
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …

Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial

HL Kaufman, J Russell, O Hamid, S Bhatia… - The lancet …, 2016 - thelancet.com
Background Merkel cell carcinoma is a rare, aggressive skin cancer with poor prognosis in
patients with advanced disease. Current standard care uses various cytotoxic chemotherapy …

[HTML][HTML] Merkel cell carcinoma: epidemiology, prognosis, therapy and unmet medical needs

D Schadendorf, C Lebbé, A Zur Hausen… - European journal of …, 2017 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer that is associated with Merkel cell
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …

Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after≥ 1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical …

HL Kaufman, JS Russell, O Hamid, S Bhatia… - … for immunotherapy of …, 2018 - Springer
Background Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer associated with
poor survival outcomes in patients with distant metastatic disease (mMCC). In an initial …

[HTML][HTML] Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN …

SP D'Angelo, S Bhatia, AS Brohl, O Hamid… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer associated with
a high risk of metastasis. In 2017, avelumab (anti–programmed death-ligand 1 (PD-L1)) …

MicroRNA dysregulations in Merkel cell carcinoma: Molecular mechanisms and clinical applications

C Mazziotta, CF Cervellera, C Lanzillotti… - Journal of Medical …, 2023 - Wiley Online Library
Merkel cell carcinoma (MCC) is an aggressive skin malignancy with two distinct etiologies.
The first, which accounts for the highest proportion, is caused by Merkel cell polyomavirus …

Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinoma

P Nghiem, HL Kaufman, M Bharmal, L Mahnke… - Future …, 2017 - Taylor & Francis
Aim: Merkel cell carcinoma (MCC) is a rare neuroendocrine, cutaneous malignancy with
poor prognosis once metastasized. The aim of this study was to conduct a systematic …

Electrochemotherapy of superficial tumors–Current status:: Basic principles, operating procedures, shared indications, and emerging applications

LG Campana, D Miklavčič, G Bertino, R Marconato… - Seminars in …, 2019 - Elsevier
Abstract Treatment of superficial tumors with electrochemotherapy (ECT) has shown a steep
rise over the past decade and indications range from skin cancers to locally advanced or …

Real-world treatment outcomes in patients with metastatic Merkel cell carcinoma treated with chemotherapy in the USA

CL Cowey, L Mahnke, J Espirito, C Helwig… - Future …, 2017 - Taylor & Francis
Aim: This retrospective study of patients in the USA with metastatic Merkel cell carcinoma
(mMCC) aimed to assess patient responses to second-line and later (2L+) and first-line (1L) …