Diffuse large B-cell lymphoma

S Li, KH Young, LJ Medeiros - Pathology, 2018 - Elsevier
Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma
worldwide, representing approximately 30–40% of all cases in different geographic regions …

Follicular lymphoma

A Carbone, S Roulland, A Gloghini, A Younes… - Nature reviews Disease …, 2019 - nature.com
Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL

WH Wilson, GW Wright, B Hodkinson… - Cancer cell, 2021 - cell.com
In diffuse large B cell lymphoma (DLBCL), tumors belonging to the ABC but not GCB gene
expression subgroup rely upon chronic active B cell receptor signaling for viability, a …

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report

SE Lacy, SL Barrans, PA Beer, D Painter… - Blood, The Journal …, 2020 - ashpublications.org
Based on the profile of genetic alterations occurring in tumor samples from selected diffuse
large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies …

Most non-canonical proteins uniquely populate the proteome or immunopeptidome

MVR Cuevas, MP Hardy, J Hollý, É Bonneil, C Durette… - Cell reports, 2021 - cell.com
Combining RNA sequencing, ribosome profiling, and mass spectrometry, we elucidate the
contribution of non-canonical translation to the proteome and major histocompatibility …

Precision medicine for human cancers with Notch signaling dysregulation

M Katoh, M Katoh - International journal of molecular …, 2020 - spandidos-publications.com
Abstract NOTCH1, NOTCH2, NOTCH3 and NOTCH4 are transmembrane receptors that
transduce juxtacrine signals of the delta‑like canonical Notch ligand (DLL) 1, DLL3, DLL4 …

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities

A Andrades, P Peinado, JC Alvarez-Perez… - Molecular cancer, 2023 - Springer
Hematological malignancies are a highly heterogeneous group of diseases with varied
molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) …

Germinal center‐derived lymphomas: The darkest side of humoral immunity

C Mlynarczyk, L Fontán, A Melnick - Immunological reviews, 2019 - Wiley Online Library
One of the unusual features of germinal center (GC) B cells is that they manifest many
hallmarks of cancer cells. Accordingly, most B‐cell neoplasms originate from the GC …

Extranodal diffuse large B cell lymphoma: molecular features, prognosis, and risk of central nervous system recurrence

TA Ollila, AJ Olszewski - Current treatment options in oncology, 2018 - Springer
Opinion statement Diffuse large B cell lymphoma (DLBCL) arises from extranodal organs in
about 30% of cases. Its prognosis and risk of recurrence in the central nervous system …

[HTML][HTML] MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma

JE Ramis-Zaldivar, B Gonzalez-Farre, A Nicolae… - …, 2021 - ncbi.nlm.nih.gov
Plasmablastic lymphoma (PBL) is an aggressive B-cell lymphoma with an
immunoblastic/large-cell morphology and terminal B-cell differentiation. The differential …