Triggering and resolution of inflammation in NASH
S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
Molecular pathogenesis of NASH
A Caligiuri, A Gentilini, F Marra - International journal of molecular …, 2016 - mdpi.com
Nonalcoholic steatohepatitis (NASH) is the main cause of chronic liver disease in the
Western world and a major health problem, owing to its close association with obesity …
Western world and a major health problem, owing to its close association with obesity …
Pathogenesis of NASH: the impact of multiple pathways
M Noureddin, AJ Sanyal - Current hepatology reports, 2018 - Springer
Purpose of review Advancing our understanding of the mechanisms that underlie NASH
pathogenesis. Recent findings Recent findings on NASH pathogenesis have expanded our …
pathogenesis. Recent findings Recent findings on NASH pathogenesis have expanded our …
Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
L Xie, Y Yuan, S Xu, S Lu, J Gu, Y Wang, Y Wang… - Cell reports, 2022 - cell.com
Copper deficiency has emerged to be associated with various lipid metabolism diseases,
including non-alcoholic fatty liver disease (NAFLD). However, the mechanisms that dictate …
including non-alcoholic fatty liver disease (NAFLD). However, the mechanisms that dictate …
Copper deficiency may be a leading cause of ischaemic heart disease
JJ DiNicolantonio, D Mangan, JH O'Keefe - Open heart, 2018 - openheart.bmj.com
Biological properties of copper Copper is involved in the functions of many copper-
dependent proteins, including transcriptional regulators, chaperones, oxidoreductases …
dependent proteins, including transcriptional regulators, chaperones, oxidoreductases …
The role of insufficient copper in lipid synthesis and fatty‐liver disease
The essential transition metal copper is important in lipid metabolism, redox balance, iron
mobilization, and many other critical processes in eukaryotic organisms. Genetic diseases …
mobilization, and many other critical processes in eukaryotic organisms. Genetic diseases …
The vital role of ATP citrate lyase in chronic diseases
Chronic or non-communicable diseases are the leading cause of death worldwide; they
usually result in long-term illnesses and demand long-term care. Despite advances in …
usually result in long-term illnesses and demand long-term care. Despite advances in …
Mineral metabolism and ferroptosis in non-alcoholic fatty liver diseases
Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver
disease worldwide. Minerals including iron, copper, zinc, and selenium, fulfil an essential …
disease worldwide. Minerals including iron, copper, zinc, and selenium, fulfil an essential …
Non-alcoholic fatty liver disease and nutritional implications: special focus on copper
L Antonucci, C Porcu, G Iannucci, C Balsano… - Nutrients, 2017 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by excess lipids in hepatocytes,
due to excessive fatty acid influx from adipose tissue, de novo hepatic lipogenesis, in …
due to excessive fatty acid influx from adipose tissue, de novo hepatic lipogenesis, in …
Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes
Copper (Cu) has emerged as an important modifier of body lipid metabolism. However, how
Cu contributes to the physiology of fat cells remains largely unknown. We found that …
Cu contributes to the physiology of fat cells remains largely unknown. We found that …