Cerebral autoregulation in sick infants: current insights

EMW Kooi, AE Richter - Clinics in perinatology, 2020 - perinatology.theclinics.com
The brain is important for our survival and identity. It has high metabolic demands and is
therefore particularly vulnerable to hypoxia and hypoglycemia. To prevent injury and …

Blood pressure, antihypertensive use, and late-life Alzheimer and non-Alzheimer dementia risk: An individual participant data meta-analysis

MJ Lennon, DM Lipnicki, BCP Lam, JD Crawford… - Neurology, 2024 - neurology.org
Background and Objectives Previous randomized controlled trials and longitudinal studies
have indicated that ongoing antihypertensive use in late life reduces all-cause dementia …

Impact of altered airway pressure on intracranial pressure, perfusion, and oxygenation: a narrative review

H Chen, DK Menon, BP Kavanagh - Critical Care Medicine, 2019 - journals.lww.com
Objectives: A narrative review of the pathophysiology linking altered airway pressure and
intracranial pressure and cerebral oxygenation. Data Sources: Online search of PubMed …

Diastolic blood pressure and intensive blood pressure control on cognitive outcomes: insights from the SPRINT MIND trial

C Jiang, S Li, Y Wang, Y Lai, Y Bai, M Zhao, L He… - …, 2023 - Am Heart Assoc
Background: The potential benefits or harms of intensive systolic blood pressure (BP) control
on cognitive function and cerebral blood flow in individuals with low diastolic blood pressure …

Validation of diffuse correlation spectroscopy measures of critical closing pressure against transcranial Doppler ultrasound in stroke patients

KC Wu, J Sunwoo, F Sheriff, P Farzam… - … of biomedical optics, 2021 - spiedigitallibrary.org
Abstract Significance: Intracranial pressure (ICP), variability in perfusion, and resulting
ischemia are leading causes of secondary brain injury in patients treated in the …

Nocturnal blood pressure dip and parapapillary choroidal microvasculature dropout in normal-tension glaucoma

JW Shin, YH Jo, MK Song, HJ Won, MS Kook - Scientific reports, 2021 - nature.com
Choroidal microvasculature dropout (CMvD) implies compromised optic nerve head
perfusion in glaucoma patients. However, there are conflicting findings whether office-hour …

Compensatory-reserve-weighted intracranial pressure and its association with outcome after traumatic brain injury

L Calviello, J Donnelly, D Cardim, C Robba, FA Zeiler… - Neurocritical care, 2018 - Springer
Objective We introduced 'compensatory-reserve-weighted intracranial pressure
(ICP),'named 'weightedICP'for brevity, as a variable that may better describe changes …

Baseline systolic versus diastolic blood pressure dip and subsequent visual field progression in normal-tension glaucoma

J Kwon, Y hye Jo, D Jeong, K Shon, MS Kook - Ophthalmology, 2019 - Elsevier
Purpose To investigate the impact of systolic and diastolic blood pressure (DBP) dip at
baseline on subsequent visual field (VF) progression in eyes with normal-tension glaucoma …

Cerebral haemodynamics during experimental intracranial hypertension

J Donnelly, M Czosnyka, S Harland… - Journal of Cerebral …, 2017 - journals.sagepub.com
Intracranial hypertension is a common final pathway in many acute neurological conditions.
However, the cerebral haemodynamic response to acute intracranial hypertension is poorly …

Pro-Con debate: the clinical (ir) relevance of the lower limit of cerebral autoregulation for anesthesiologists

M Czosnyka, T Santarius, J Donnelly… - Anesthesia & …, 2022 - journals.lww.com
Abstract In this Pro-Con commentary article, we discuss whether the lower limit of cerebral
autoregulation is clinically relevant for anesthesiologists. The central question regarding this …