Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care: Second update 2022

S Kietaibl, A Ahmed, A Afshari… - European Journal of …, 2023 - journals.lww.com
Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Is tranexamic acid beneficial in open spine surgery? and its effects vary by dosage, age, sites, and locations: a meta-analysis of randomized controlled trials

ZG Liu, F Yang, YH Zhu, GC Liu, QS Zhu, BY Zhang - World Neurosurgery, 2022 - Elsevier
Background The role of tranexamic acid (TXA) in controlling blood loss during spine surgery
remains unclear. With the publication of new randomized controlled trials (RCTs), we …

Tranexamic acid given into wound reduces postoperative drainage, blood loss, and hospital stay in spinal surgeries: a meta-analysis

S Hui, Y Peng, L Tao, S Wang, Y Yang, Y Du… - Journal of Orthopaedic …, 2021 - Springer
Background Although intravenous tranexamic acid administration (ivTXA) has prevailed in
clinical antifibrinolytic treatment, whether it increases thromboembolic risks has remained …

Efficacy and safety of topical tranexamic acid in spinal surgery: a systematic review and meta-analysis

H Luo, X Zhang, C Xie, L Wu, G Cai… - EFORT Open …, 2024 - eor.bioscientifica.com
Purpose This study aimed to assess the effects of topical tranexamic acid (tTXA) in spinal
surgery to provide reliable clinical evidence for its usefulness. Methods The PubMed …

Efficacy and safety of postoperative intravenous tranexamic acid in total knee arthroplasty: a prospective randomized controlled study

C Xue, Y Yao, H Lv, L Cheng, J Jing - Orthopaedic Surgery, 2021 - Wiley Online Library
Objective To assess the efficacy and safety of postoperative intravenous tranexamic acid
(TXA) in patients undergoing total knee arthroplasty (TKA). Methods From March 2020 to …

[HTML][HTML] Safety and efficacy of high-dose tranexamic acid in spine surgery: a retrospective single-institution series

NJ Brown, Z Pennington, AS Himstead, CY Yang… - World Neurosurgery, 2023 - Elsevier
Objective Currently, tranexamic acid (TXA) is the most widely used antifibrinolytic agent in
spine surgery and has been proven to reduce perioperative blood loss. However, the safety …

[HTML][HTML] Does the use of tranexamic acid intraoperatively reduce postoperative blood loss and complications following biportal endoscopic lumbosacral …

A Upfill-Brown, T Olson, B Adejuyigbe… - Journal of Spine …, 2024 - ncbi.nlm.nih.gov
Background Biportal endoscopic spine surgery is an effective minimally invasive technique
for treating common lumbar pathologies. We aim to evaluate the impact of intraoperative …

Does obesity correlate with postoperative complications after elective posterior cervical spine fusion?

N Fatima, E Massaad, C Alvarez-Breckenridge… - World neurosurgery, 2020 - Elsevier
Background With the increasing prevalence of obesity, there is a need to understand the
impact of body mass index (BMI) on spine surgery outcomes. Previous literature has …

Topical tranexemic acid reduces intra-operative blood loss and transfusion requirements in spinal deformity correction in patients with adolescent idiopathic scoliosis

S George, S Ramchandran, A Mihas, K George… - Spine Deformity, 2021 - Springer
Purpose To evaluate the effectiveness of the use of topical tranexamic acid (tTXA) in spinal
deformity correction in AIS patients Methods Sixty consecutive operative AIS patients were …

Intravenous versus topical tranexamic acid in spinal surgery: a systematic review and meta-analysis

B Deng, X Li, P Xie, X Luo, X Yan - Journal of Orthopaedic Surgery and …, 2024 - Springer
Background The administration of tranexamic acid (TXA) during spinal surgery has been
shown to reduce blood loss. However, the efficacy and safety of intravenous TXA (ivTXA) …