Vancomycin plus piperacillin-tazobactam and acute kidney injury in adults: a systematic review and meta-analysis

MK Luther, TT Timbrook, AR Caffrey, D Dosa… - Critical care …, 2018 - journals.lww.com
Objectives: The objective of this systematic review and meta-analysis was to assess acute
kidney injury with combination therapy of vancomycin plus piperacillin-tazobactam, in …

Antibiotic use in the intensive care unit: optimization and de-escalation

M Campion, G Scully - Journal of intensive care medicine, 2018 - journals.sagepub.com
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes.
Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay …

Principles and practice of antibiotic stewardship in the ICU

CI Pickens, RG Wunderink - Chest, 2019 - Elsevier
In the face of emerging drug-resistant pathogens and a decrease in the development of new
antimicrobial agents, antibiotic stewardship should be practiced in all critical care units …

Systematic review of applied usability metrics within usability evaluation methods for hospital electronic healthcare record systems: Metrics and Evaluation Methods for …

MW Wronikowska, J Malycha… - Journal of Evaluation …, 2021 - Wiley Online Library
Background and objectives Electronic healthcare records have become central to patient
care. Evaluation of new systems include a variety of usability evaluation methods or usability …

Evaluation of an opt-out protocol for antibiotic de-escalation in patients with suspected sepsis: a multicenter, randomized, controlled trial

RW Moehring, ME Yarrington… - Clinical Infectious …, 2023 - academic.oup.com
Background Sepsis guidelines recommend daily review to de-escalate or stop antibiotics in
appropriate patients. This randomized, controlled trial evaluated an opt-out protocol to …

Decreases in antimicrobial use associated with multihospital implementation of electronic antimicrobial stewardship tools

CJ Graber, MM Jones, MB Goetz… - Clinical Infectious …, 2020 - academic.oup.com
Background Antimicrobial stewards may benefit from comparative data to inform
interventions that promote optimal inpatient antimicrobial use. Methods Antimicrobial …

Impact of a prescriber-driven antibiotic time-out on antibiotic use in hospitalized patients

KA Thom, PD Tamma, AD Harris… - Clinical Infectious …, 2019 - academic.oup.com
A multicenter quasi-experimental study of a provider-driven antibiotic “time-out” in 3470
antibiotic courses showed no difference in antibiotic use before and after implementation …

Optimizing antimicrobial therapy in urinary tract infections: a focus on urine culture and sensitivity testing

R Alkhawaldeh, R Abu Farha… - Frontiers in …, 2022 - frontiersin.org
Objectives: This cross-sectional study was conducted at Jordan university hospital to
evaluate the impact of microbial culture data and sensitivity results on optimizing UTI …

Role of technology in antimicrobial stewardship

DN Bremmer, TL Trienski, TL Walsh… - Medical …, 2018 - medical.theclinics.com
Because of the increasing plague of antimicrobial resistance (AR) and antibiotic misuse,
antimicrobial stewardship programs (ASPs) are now a mandatory entity in all US hospitals …

A value set for documenting adverse reactions in electronic health records

FR Goss, KH Lai, M Topaz, WW Acker… - Journal of the …, 2018 - academic.oup.com
Objective To develop a comprehensive value set for documenting and encoding adverse
reactions in the allergy module of an electronic health record. Materials and Methods We …