High-speed atomic force microscopy for nano-visualization of dynamic biomolecular processes

T Ando, T Uchihashi, T Fukuma - Progress in Surface Science, 2008 - Elsevier
The atomic force microscope (AFM) has a unique capability of allowing the high-resolution
imaging of biological samples on substratum surfaces in physiological solutions. Recent …

Model cell membranes: Techniques to form complex biomimetic supported lipid bilayers via vesicle fusion

GJ Hardy, R Nayak, S Zauscher - Current opinion in colloid & interface …, 2013 - Elsevier
Vesicle fusion has long provided an easy and reliable method to form supported lipid
bilayers (SLBs) from simple, zwitterionic vesicles on siliceous substrates. However, for …

[HTML][HTML] Dividing cells regulate their lipid composition and localization

GE Atilla-Gokcumen, E Muro, J Relat-Goberna… - Cell, 2014 - cell.com
Although massive membrane rearrangements occur during cell division, little is known about
specific roles that lipids might play in this process. We report that the lipidome changes with …

Mesoporous silica nanoparticle-supported lipid bilayers (protocells) for active targeting and delivery to individual leukemia cells

PN Durfee, YS Lin, DR Dunphy, AJ Muñiz, KS Butler… - ACS …, 2016 - ACS Publications
Many nanocarrier cancer therapeutics currently under development, as well as those used
in the clinical setting, rely upon the enhanced permeability and retention (EPR) effect to …

Preparation of DOPC and DPPC supported planar lipid bilayers for atomic force microscopy and atomic force spectroscopy

SJ Attwood, Y Choi, Z Leonenko - International journal of molecular …, 2013 - mdpi.com
Cell membranes are typically very complex, consisting of a multitude of different lipids and
proteins. Supported lipid bilayers are widely used as model systems to study biological …

[图书][B] Atomic force microscopy for biologists

VJ Morris, AR Kirby, PA Gunning - 2009 - books.google.com
Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for
biologists which offer the magnification range of both the light and electron microscope, but …

Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques

LA Clifton, RA Campbell, F Sebastiani… - Advances in Colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …

Influence of cholesterol on the phase transition of lipid bilayers: a temperature-controlled force spectroscopy study

L Redondo-Morata, MI Giannotti, F Sanz - Langmuir, 2012 - ACS Publications
Cholesterol (Chol) plays the essential function of regulating the physical properties of the
cell membrane by controlling the lipid organization and phase behavior and, thus, managing …

Fusion dynamics of cubosome nanocarriers with model cell membranes

BP Dyett, H Yu, J Strachan, CJ Drummond… - Nature …, 2019 - nature.com
Drug delivery with nanocarriers relies on the interaction of individual nanocarriers with the
cell surface. For lipid-based NCs, this interaction uniquely involves a process of membrane …

Effect of NaCl and KCl on phosphatidylcholine and phosphatidylethanolamine lipid membranes: insight from atomic-scale simulations for understanding salt-induced …

AA Gurtovenko, I Vattulainen - The Journal of Physical Chemistry …, 2008 - ACS Publications
To gain a better understanding of how monovalent salt under physiological conditions
affects plasma membranes, we have performed 200 ns atomic-scale molecular dynamics …