Inflammation is an integral part of animal biology. It provides critical protection from adverse
environmental factors by enforcing the defense of homeostasis and the functional and …

Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …

Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

The RNA-editing enzyme ADAR1 is essential for the suppression of innate immune
activation and pathology caused by aberrant recognition of self-RNA, a role it carries out by …

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer's
disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in …

Active cell death, in its many forms, is a fundamental biological process. Studies over the
past several decades have explored the functions and consequences of cellular demise and …

Macrophages stand in the first line of defense against a variety of pathogens but are also
involved in the maintenance of tissue homeostasis. To fulfill their functions macrophages …

It is currently not well known how necroptosis and necroptosis responses manifest in vivo.
Here, we uncovered a molecular switch facilitating reprogramming between two alternative …

The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …