Directed evolution: methodologies and applications
Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …
and systems in a test tube through iterative rounds of gene diversifications and library …
Application of combinatorial optimization strategies in synthetic biology
G Naseri, MAG Koffas - Nature communications, 2020 - nature.com
In the first wave of synthetic biology, genetic elements, combined into simple circuits, are
used to control individual cellular functions. In the second wave of synthetic biology, the …
used to control individual cellular functions. In the second wave of synthetic biology, the …
A biological camera that captures and stores images directly into DNA
The increasing integration between biological and digital interfaces has led to heightened
interest in utilizing biological materials to store digital data, with the most promising one …
interest in utilizing biological materials to store digital data, with the most promising one …
A red light–responsive photoswitch for deep tissue optogenetics
Y Kuwasaki, K Suzuki, G Yu, S Yamamoto… - Nature …, 2022 - nature.com
Red light penetrates deep into mammalian tissues and has low phototoxicity, but few
optogenetic tools that use red light have been developed. Here we present MagRed, a red …
optogenetic tools that use red light have been developed. Here we present MagRed, a red …
Multidimensional characterization of inducible promoters and a highly light-sensitive LOV-transcription factor
The ability to independently control the expression of different genes is important for
quantitative biology. Using budding yeast, we characterize GAL1pr, GALL, MET3pr, CUP1pr …
quantitative biology. Using budding yeast, we characterize GAL1pr, GALL, MET3pr, CUP1pr …
Sensing the future of bio-informational engineering
The practices of synthetic biology are being integrated into 'multiscale'designs enabling two-
way communication across organic and inorganic information substrates in biological, digital …
way communication across organic and inorganic information substrates in biological, digital …
Combinatorial optimization of gene expression through recombinase-mediated promoter and terminator shuffling in yeast
C Cautereels, J Smets, P Bircham… - Nature …, 2024 - nature.com
Microbes are increasingly employed as cell factories to produce biomolecules. This often
involves the expression of complex heterologous biosynthesis pathways in host strains …
involves the expression of complex heterologous biosynthesis pathways in host strains …
The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
[PDF][PDF] Tasting the terroir of wine yeast innovation
IS Pretorius - FEMS yeast research, 2020 - academic.oup.com
Wine is an archetypal traditional fermented beverage with strong territorial and socio-cultural
connotations. Its 7000 year history is patterned by a tradition of innovation. Every value …
connotations. Its 7000 year history is patterned by a tradition of innovation. Every value …
Heterozygous diploid and interspecies SCRaMbLEing
Abstract SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-
mediated Evolution) is a genome restructuring technique that can be used in synthetic …
mediated Evolution) is a genome restructuring technique that can be used in synthetic …