Venous abnormalities contribute to the pathophysiology of several neurological conditions.
This paper reviews the literature regarding venous abnormalities in multiple sclerosis (MS) …

There is neuropathologic evidence that confluent MRI white matter lesions in the elderly
reflect ischemic brain damage due to microangiopathy. The authors hypothesize that …

Both axon and myelin degeneration have significant impact on the long-term disability of
patients with white matter disorder. However, the clinical manifestations of the neurological …

Background and aim The pathogenesis of cerebral small-vessel disease (SVD) is
incompletely understood. Endothelial dysfunction has been implicated and may result in …

White matter hyperintensities (WMHs) are a frequent finding on T2‐weighted MRI of the
brain in elderly individuals, but their prevalence and severity in younger asymptomatic …

The aim of this study is to propose methods for assessing the reproducibility of diffusion
tractography algorithms in future clinical studies and to show their application to the …

Objective: To investigate whether the extent of white matter lesions (WML) on fluid
attenuated inversion recovery (FLAIR) MRI sequences is an independent risk factor for …

Background and Purpose—Reduced cerebrovascular reactivity (CVR) with steal
phenomenon is an independent predictor for stroke and may indicate tissue exposed to …

Background and Purpose—The National Institutes of Health Stroke Scale (NIHSS) provides
a reliable, quantitative measure of ischemic stroke severity and is predicted by the infarct …

Objective: To assess normal-appearing white matter (NAWM) characteristics by magnetic
resonance spectroscopy (MRS) and diffusion-weighted imaging (DWI) in elderly subjects …