Impact of arterial stiffness on cerebrovascular function: a review of evidence from humans and preclinical models
With advancing age, the cerebral vasculature becomes dysfunctional, and this dysfunction is
associated with cognitive decline. However, the initiating cause of these age-related …
associated with cognitive decline. However, the initiating cause of these age-related …
Age-associated increases in middle cerebral artery pulsatility differ between men and women
WK Lefferts, KS Reed, RE Rosonke… - American Journal …, 2023 - journals.physiology.org
Mechanisms underlying sex differences in brain aging remain unclear but may relate to
changes in cerebral pulsatile blood flow. Sex differences in the stiffening of the large arteries …
changes in cerebral pulsatile blood flow. Sex differences in the stiffening of the large arteries …
Effects of aerobic exercise training on cerebral pulsatile hemodynamics in middle-aged adults with elevated blood pressure/stage 1 hypertension
KS Reed, AM Frescoln, Q Keleher… - Journal of Applied …, 2024 - journals.physiology.org
Mechanisms behind the protective effects of aerobic exercise on brain health remain elusive
but may be vascular in origin and relate to cerebral pulsatility. This pilot study investigated …
but may be vascular in origin and relate to cerebral pulsatility. This pilot study investigated …
[HTML][HTML] Vascular function in women: when studying perimenopause is peri important
LE DuBose, WK Lefferts - Experimental physiology, 2023 - ncbi.nlm.nih.gov
The menopause transition is a time of accelerated cardiovascular aging and increased
susceptibility to chronic diseases including cardiovascular disease (CVD). Growing data …
susceptibility to chronic diseases including cardiovascular disease (CVD). Growing data …
[HTML][HTML] Acute Effects of a Maximal Cardiopulmonary Exercise Test on Cardiac Hemodynamic and Cerebrovascular Response and Their Relationship with Cognitive …
Cardiovascular and cerebrovascular diseases are prevalent in individuals with type 2
diabetes (T2D). Among people with T2D aged over 70 years, up to 45% might have …
diabetes (T2D). Among people with T2D aged over 70 years, up to 45% might have …
Determinants of cerebral blood flow and arterial transit time in healthy older adults
Cerebral blood flow (CBF) and arterial transit time (ATT), markers of brain vascular health,
worsen with age. The primary aim of this cross-sectional study was to identify modifiable …
worsen with age. The primary aim of this cross-sectional study was to identify modifiable …