Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, is considered
a neglected tropical disease by the World Health Organization. Congenital transmission of …

Considering the extensive and widespread impact on individuals, cancer can presently be
categorized as a pandemic. In many instances, the development of tumors has been linked …

Chronic arsenic exposure is a risk factor for human fatty liver disease, and the ERK signaling
pathway plays an important role in the regulation of liver lipid metabolism. However, whether …

Introduction Toxoplasma gondii is the etiologic agent of toxoplasmosis, a disease that affects
about one-third of the human population. Most infected individuals are asymptomatic, but …

Abstract Introduction Upon infection, Trypanosoma cruzi, a protozoan parasite, crosses the
placental barrier and causes congenital Chagas disease. Ex vivo infection of human …

Few major advances in fighting parasitic diseases have been made in China since the
development of new methods for prevention, control, and elimination. However, the …

Abstract Purpose of Review Why around 5% of Trypanosoma cruzi–infected pregnant
women transmit the parasite to their offspring whereas 95% do not? Answers to this main …

Abstract Background Congenital Chagas disease is caused by the protozoan parasite
Trypanosoma cruzi that must cross the placental barrier during transmission. The …

Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas Disease (CD), is transmitted to
humans by infected kissing bugs, blood transfusion, organ transplantation, and from mother …

The constitutive activation of ERK1/2 (RAF-MEK-ERK) signaling pathway has been widely
observed in many types of tumors, and the blockade of ERK1/2 signaling pathway has been …