Computational lung modelling in respiratory medicine

S Neelakantan, Y Xin, DP Gaver… - Journal of The …, 2022 - royalsocietypublishing.org
Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Technical standards for respiratory oscillometry

GG King, J Bates, KI Berger, P Calverley… - European …, 2020 - Eur Respiratory Soc
Oscillometry (also known as the forced oscillation technique) measures the mechanical
properties of the respiratory system (upper and intrathoracic airways, lung tissue and chest …

[HTML][HTML] Intra-breath oscillometry for assessing respiratory outcomes

Z Hantos - Current Opinion in Physiology, 2021 - Elsevier
Respiratory oscillometry (also known as the forced oscillation technique) is increasingly
contributing to lung function studies in clinical routine and research, as a result of its …

Bronchodilator response assessed by the forced oscillation technique identifies poor asthma control with greater sensitivity than spirometry

AM Cottee, LM Seccombe, C Thamrin, GG King… - Chest, 2020 - Elsevier
Background Persistent bronchodilator response (BDR) following diagnosis of asthma is an
underrecognized treatable trait, associated with worse lung function and asthma control. The …

[HTML][HTML] Comparison of oscillometry devices using active mechanical test loads

RJ Dandurand, JP Lavoie, LC Lands… - ERJ Open …, 2019 - Eur Respiratory Soc
Noninvasiveness, low cooperation demand and the potential for detailed physiological
characterisation have promoted the use of oscillometry in the assessment of lung function …

[HTML][HTML] Lung stiffness of C57BL/6 versus BALB/c mice

A Rojas-Ruiz, M Boucher, R Gill, L Gélinas, FQ Tom… - Scientific Reports, 2023 - nature.com
This study was undertaken to determine whether a smaller lung volume or a stiffer lung
tissue accounts for the greater lung elastance of C57BL/6 than BALB/c mice. The …

[HTML][HTML] Atelectrauma versus volutrauma: a tale of two time-constants

JHT Bates, DP Gaver, NM Habashi… - Critical care …, 2020 - journals.lww.com
Objectives: Elucidate how the degree of ventilator-induced lung injury due to atelectrauma
that is produced in the injured lung during mechanical ventilation is determined by both the …

[HTML][HTML] Clinical application of forced oscillation technique (FOT) in early detection of airway changes in smokers

P Bhattarai, S Myers, C Chia, HC Weber… - Journal of clinical …, 2020 - mdpi.com
The forced oscillation technique (FOT) is a non-invasive method to assess airway function
by emitting oscillatory signals into the respiratory tract during tidal ventilation. This opinion …

[HTML][HTML] Determination of reliable lung function parameters in intubated mice

E Bonnardel, R Prevel, M Campagnac, M Dubreuil… - Respiratory …, 2019 - Springer
Background Animal models and, in particular, mice models, are important tools to
investigate the pathogenesis of respiratory diseases and to test potential new therapeutic …

[HTML][HTML] Dismantling airway disease with the use of new pulmonary function indices

SC Zimmermann, KO Tonga… - European Respiratory …, 2019 - Eur Respiratory Soc
We are currently limited in our abilities to diagnose, monitor disease status and manage
chronic airway disease like asthma and chronic obstructive pulmonary disease (COPD) …